Results 71 to 80 of about 739,590 (261)

Comparative assessment of respiratory, hematological and inflammatory profiles of long-term users of cigarettes, shisha, and e-cigarettes in Saudi Arabia

Tobacco Induced Diseases
Introduction Globally, over 1 billion people smoke, resulting in approximately 8 million deaths each year. Although the health risks associated with traditional cigarettes are extensively documented, there is an increasing need to evaluate the long-term ...
Mazen M. Homoud, Rowaida Qoutah, Gokul Krishna, Noran Harbli, Layan Saaty, Afrah Obaidan, Abdulrahman Alkhathami, Noran Jamil, Tala Μ. Alkayyat, Maryam Alsughayyir, Nada Gubari, Saleh Alkhathami, Ali Alqarni, Omar Alqurashi, Khalid Assiri, Khalid Saeed Alwadeai, Wafaa Abdulrahman, Husam Alahmadi, Ayedh Alahmari   +18 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Daytime sleepiness and academic performance among respiratory therapy students in Saudi Arabia: a cross-sectional survey

Discover Applied Sciences
Background Excessive daytime sleepiness (EDS) is a prevalent concern among health-related students, but its incidence and impact on academic performance remain unexplored in undergraduate respiratory therapy (RT) students in Saudi Arabia. This study aims
Mohammed M. Alyami, Ahmed H. Alasimi, Shahad Z. Albadani, Areen M. Alshehri, Rana A. Alqahtani, Abdullah A. Alqarni, Jaber S. Alqahtani, Abdallah Y. Naser, Hassan Alwafi, Saeed M. Alghamdi, Mansour S. Majrshi, Rayan A. Siraj, Abdulelah M. Aldhahir   +12 more
doaj   +1 more source

Quality indicators in respiratory therapy

World Journal of Critical Care Medicine
Quality indicators in healthcare refer to measurable and quantifiable parameters used to assess and monitor the performance, effectiveness, and safety of healthcare services. These indicators provide a systematic way to evaluate the quality of care offered, and thereby to identify areas for improvement and to ensure that patient care meets established ...
Karthika, Manjush, Vanajakshy Kumaran, Sureshkumar, Beekanahaali Mokshanatha, Praveen   +2 more
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Exploring research barriers, priorities and perceptions among respiratory therapists in Asia: a cross-sectional study

BMC Medical Education
Background Respiratory therapists (RT) are healthcare professionals who receive specialized training to apply evidence-based practices in managing pulmonary disorders. Despite global expansion of RT programs across Asia, there is only limited RT-specific
Gokul G. Krishna, Ann M. Jose, Weaam Rahali, Majed Alkahtani, Ziyad M. Alshahrani, Mazen M. Homoud, Mohammed Almeshari, Khalid S. Alwadeai, Mohammed Dhafer Alahmari, Ayedh Dhafer Alahmari   +9 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Using Remote Technology to Engage Patients with Interstitial Lung Diseases in a Home Exercise Program: A Pilot Study

Life
Introduction: The access and compliance of patients with interstitial lung diseases (ILDs) to exercise programs (EPs) remain challenges. Objectives: We assessed the dropout rate, intervention completion, compliance with data acquisition and submission ...
Antonio Sarmento, Kaitlin King, Diana C. Sanchez-Ramirez   +2 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Patterns and characteristics of nicotine pouch use among adults with a history of cigarette smoking

Frontiers in Public Health
BackgroundNicotine pouches (NP) are emerging as a potentially safer alternative to tobacco smoking. However, data on NP users with a history of tobacco smoking are limited.
Hajed M. Al-Otaibi, Hajed M. Al-Otaibi, Malik A. Althobiani, Malik A. Althobiani, Malik A. Althobiani   +4 more
doaj   +1 more source