Results 101 to 110 of about 1,320,014 (285)

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? [PDF]

, 2019
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the ...
Lajoie, Louise, Dubé, Mathieu, Alain Le Coupanec, Mathieu Dubé, Desforges, Marc, Marc Desforges, Pierre J. Talbot, Dubeau, Philippe, Andréanne Bourgouin, Louise Lajoie, Talbot, Pierre, Le Coupanec, Alain, Philippe Dubeau, Bourgouin, Andréanne, Talbot, Pierre J.   +14 more
core   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

Advanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee, Xinyi Wang, Sirui Li, Jihyang Park, Hyunseok Lee, Jianting Yao, Kedar Narayan, Yuqi Wang, Jiashu Ren, Yueqi Deng, Salahuddin Ahmed, Denver I. Greenawalt, Archana Pandiyan, Loganathan Veeramuthu, Chi‐Ching Kuo, Tao Zhou   +15 more
wiley   +1 more source

Impact of COVID‐19 on Respiratory Virus Infections in Children, Japan, 2018–2023

Immunity, Inflammation and Disease
Background COVID‐19, caused by SARS‐CoV‐2, was first documented in Japan in January 2020. We previously reported an increased risk of rhinovirus infections among children during the early phase of the COVID‐19 pandemic.
Emi Takashita, Kohei Shimizu, Chiharu Kawakami, Tomoko Momoki, Miwako Saikusa, Hiroki Ozawa, Makoto Kumazaki, Shuzo Usuku, Nobuko Tanaka, Ryuichi Senda, Ichiro Okubo, Seiichiro Fujisaki, Shiho Nagata, Hiroko Morita, Hideka Miura, Kayo Watanabe, Mina Nakauchi, Yoko Matsuzaki, Shinji Watanabe, Hideki Hasegawa, Yoshihiro Kawaoka   +20 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Multiplexed Detection of Respiratory Viruses Using Surface Plasmon Resonance Spectroscopy With Ultrathin Carbon Nanomembranes

Advanced Healthcare Materials, EarlyView.
An ultrathin azide‐functionalized carbon nanomembrane (N3‐CNM) provides a versatile biointerface for antibody immobilization on gold SPR sensors. Integrated with a multichannel SPR platform, the functionalized surface enables label‐free, simultaneous detection of SARS‐CoV‐2, Influenza A, and RSV antigens, demonstrating the potential of CNM‐based ...
Ghazaleh Eshaghi, Hamid Reza Rasouli, David Kaiser, Tobias Fischer, Katrin Frankenfeld, Abhishek Sharma, Andrey Turchanin   +6 more
wiley   +1 more source

The Global Influenza Hospital Surveillance Network: A Multicountry Public Health Collaboration [PDF]

Respiratory viruses represent a significant public health threat. There is the need for robust and coordinated surveillance to guide global health responses.
Sordillo, Emilia, Draganescu, Anca Cristina, Viboud, Cecile, Bresee, Joseph, Cowling, Ben, Regue, Hadrien, Commaille-Chapus, Catherine, Chaves, Sandra S, Otieno, Nancy A, Orrico-Sanchez, Alejandro, Nugyen, Liem Binh Luong, Burtseva, Elena, Baillie, Vicky, Destras, Gregory, Koul, Parvaiz A., ÜNAL, SERHAT, Chaves, Sandra S., Raboni, Sonia M, Salah, Afif Ben, Gomez-Camargo, Doris, Ruiz-Palacios, Guillermo M, Sandulescu, Oana, Mira-Iglesias, Ainara, McCauley, John W, Giamberardino, Heloisa I. G., Mironenko, Alla, Lopez-Labrador, F. Xavier, Mahe, Cedric, DURUSU TANRIÖVER, MİNE, Dbaibo, Ghassan, Andrew, Melissa K., Dia, Ndongo, Badar, Nazish, Lina, Bruno, Raboni, Sonia M., Sominina, Anna, Zhang, Wenqing, Josset, Laurence, Nunes, Marta C, Otieno, Nancy A., Ortiz, Justin R., Bal, Antonin, Salman, Muhammad, Nitsch-Osuch, Aneta, Laguna-Torres, Victor Alberto, Mcneil, Shelly, Ortiz, Justin R, van Bakel, Harm, Baral, Kedar, Simon, Viviana, Vanhems, Philippe, Zhang, Tao, Torcel-Pagnon, Laurence, Giamberardino, Heloisa I  G, Medic, Snezana, Danilenko, Daria, Tanriover, Mine Durusu, Launay, Odile, López-Labrador, F.  Xavier, Hunsinger, Camille, Boutros, Celina, Mccauley, John W., Baumeister, Elsa, Koul, Parvaiz A, Coulibaly, Daouda, Chauvel, Cecile, Ruiz-Palacios, Guillermo M., Kyncl, Jan, Andrew, Melissa K, Nunes, Marta C.   +69 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Nature Communications, 2019
Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al.
Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach   +14 more
doaj   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source