Results 111 to 120 of about 297,224 (307)

Impact of COVID‐19 on Respiratory Virus Infections in Children, Japan, 2018–2023

Immunity, Inflammation and Disease
Background COVID‐19, caused by SARS‐CoV‐2, was first documented in Japan in January 2020. We previously reported an increased risk of rhinovirus infections among children during the early phase of the COVID‐19 pandemic.
Emi Takashita, Kohei Shimizu, Chiharu Kawakami, Tomoko Momoki, Miwako Saikusa, Hiroki Ozawa, Makoto Kumazaki, Shuzo Usuku, Nobuko Tanaka, Ryuichi Senda, Ichiro Okubo, Seiichiro Fujisaki, Shiho Nagata, Hiroko Morita, Hideka Miura, Kayo Watanabe, Mina Nakauchi, Yoko Matsuzaki, Shinji Watanabe, Hideki Hasegawa, Yoshihiro Kawaoka   +20 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? [PDF]

, 2019
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the ...
Lajoie, Louise, Dubé, Mathieu, Alain Le Coupanec, Mathieu Dubé, Desforges, Marc, Marc Desforges, Pierre J. Talbot, Dubeau, Philippe, Andréanne Bourgouin, Louise Lajoie, Talbot, Pierre, Le Coupanec, Alain, Philippe Dubeau, Bourgouin, Andréanne, Talbot, Pierre J.   +14 more
core   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Nature Communications, 2019
Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al.
Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach   +14 more
doaj   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source

Clinical and laboratory characteristics of patients hospitalized with severe COVID-19 in New Orleans, August 2020 to September 2021

Scientific Reports
Louisiana experienced high morbidity and mortality from COVID-19. To assess possible explanatory factors, we conducted a cohort study (ClinSeqSer) of patients hospitalized with COVID-19 in New Orleans during August 2020–September 2021.
Arnaud Drouin, Ian D. Plumb, Matthew McCullough, Jade James Gist, Sharon Liu, Marc Theberge, Joshua Katz, Matthew Moreida, Shelby Flaherty, Bhoomija Chatwani, Melissa Briggs Hagen, Claire M. Midgley, Dahlene Fusco   +12 more
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

The Global Influenza Hospital Surveillance Network: A Multicountry Public Health Collaboration [PDF]

Respiratory viruses represent a significant public health threat. There is the need for robust and coordinated surveillance to guide global health responses.
Sordillo, Emilia, Draganescu, Anca Cristina, Viboud, Cecile, Bresee, Joseph, Cowling, Ben, Regue, Hadrien, Commaille-Chapus, Catherine, Chaves, Sandra S, Otieno, Nancy A, Orrico-Sanchez, Alejandro, Nugyen, Liem Binh Luong, Burtseva, Elena, Baillie, Vicky, Destras, Gregory, Koul, Parvaiz A., ÜNAL, SERHAT, Chaves, Sandra S., Raboni, Sonia M, Salah, Afif Ben, Gomez-Camargo, Doris, Ruiz-Palacios, Guillermo M, Sandulescu, Oana, Mira-Iglesias, Ainara, McCauley, John W, Giamberardino, Heloisa I. G., Mironenko, Alla, Lopez-Labrador, F. Xavier, Mahe, Cedric, DURUSU TANRIÖVER, MİNE, Dbaibo, Ghassan, Andrew, Melissa K., Dia, Ndongo, Badar, Nazish, Lina, Bruno, Raboni, Sonia M., Sominina, Anna, Zhang, Wenqing, Josset, Laurence, Nunes, Marta C, Otieno, Nancy A., Ortiz, Justin R., Bal, Antonin, Salman, Muhammad, Nitsch-Osuch, Aneta, Laguna-Torres, Victor Alberto, Mcneil, Shelly, Ortiz, Justin R, van Bakel, Harm, Baral, Kedar, Simon, Viviana, Vanhems, Philippe, Zhang, Tao, Torcel-Pagnon, Laurence, Giamberardino, Heloisa I  G, Medic, Snezana, Danilenko, Daria, Tanriover, Mine Durusu, Launay, Odile, López-Labrador, F.  Xavier, Hunsinger, Camille, Boutros, Celina, Mccauley, John W., Baumeister, Elsa, Koul, Parvaiz A, Coulibaly, Daouda, Chauvel, Cecile, Ruiz-Palacios, Guillermo M., Kyncl, Jan, Andrew, Melissa K, Nunes, Marta C.   +69 more
core   +1 more source