Results 161 to 170 of about 436,283 (306)

Immunosenescence and susceptibility to respiratory viruses: a state-of-the-art review. [PDF]

Eur Respir Rev
Fragkou PC, Skevaki C, Moschopoulos CD, Keske Ş, Wozniak H, Malézieux-Picard A, Prendki V, Rello J, ESCMID Study Group for Respiratory Viruses (ESGREV) and the ESCMID Study Group for Infections in the Elderly (ESGIE).   +8 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Editorial: Emerging concepts for respiratory viruses after the pandemic. [PDF]

Front Cell Infect Microbiol
Dimopoulou D, Skevaki C, Can F, Morfin-Sherpa F, Fragkou PC.   +4 more
europepmc   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Streamlining protocols for the establishment of a physical biobank of respiratory viruses in the Philippines. [PDF]

J Transl Med
Reyes-Haygood SJ, Rala-Ramos L, Balgos Pada-On JE, Pigao EC, Nicole Perreras MA, Tongol AF, Leon A, Alonzo-Dimamay MT.   +7 more
europepmc   +1 more source

Respiratory viruses

, 2012
Korsman, Stephen N.J., van Zyl, Gert U., Nutt, Louise, Andersson, Monique I., Preiser, Wolfgang   +4 more
openaire   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

Advanced Science, EarlyView.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah, Denver P. Linklater, Vassil Tzanov, Chaitali Dekiwadia, Sergey Rubanov, Phuc H. Le, Laleh Tafakori, Ranya Simons, Graeme Moad, Soichiro Saita, Takashi Yanagishita, Hideki Masuda, Vladimir Baulin, Natalie A. Borg, Elena P. Ivanova   +14 more
wiley   +1 more source

Editorial: Immunological regulation to enteroviruses and respiratory viruses: infection and vaccination responses. [PDF]

Front Immunol
Zheng H.
europepmc   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Ultrasound effectively destabilizes and disrupts the structural integrity of enveloped respiratory viruses. [PDF]

Sci Rep
Veras FP, Nakamura G, Pereira-da-Silva MA, Ruiz GCM, Constantino CJL, Martins R, Arruda E, Cunha FQ, Bruno OM.   +8 more
europepmc   +1 more source