Results 161 to 170 of about 3,116,161 (404)

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Surveillance of respiratory viruses in the outpatient setting in rural coastal Kenya: baseline epidemiological observations

Wellcome Open Research, 2018
Background: Endemic and seasonally recurring respiratory viruses are a major cause of disease and death globally. The burden is particularly severe in developing countries.
J. Nyiro, P. Munywoki, E. Kamau, C. Agoti, Alex Gichuki, T. Etyang, G. Otieno, D. Nokes   +7 more
semanticscholar   +1 more source

Label‐Free Sensing of Coronaviral Sequences via Kretschmann‐Configuration Reflectance Spectroscopic Ellipsometry: Sensitivity, Specificity, and Interfacial Effects

Advanced Materials Interfaces, EarlyView.
Spectroscopic ellipsometry in the Kretschmann‐Raether configuration (KRSE) is employed to characterize a DNA‐functionalized platform for viral sequence recognition. By merging SE with surface plasmon resonance, KRSE outperforms conventional SE, achieving nanomolar targeting through resonance wavelength shifts (δλ) measurements. Its enhanced interfacial
Silvia Maria Cristina Rotondi, Paolo Canepa, Francesco Bisio, Ornella Cavalleri, Maurizio Canepa   +4 more
wiley   +1 more source

Pre COVID-19 molecular epidemiology of respiratory syncytial virus (RSV) among children in Bangladesh

, 2022
Mohammad Enayet Hossain, Mohammed Ziaur Rahman, Md. Muzahidul Islam, Ananya Ferdous Hoque, Mariya Kibtiya Sumiya, Mst. Noorjahan Begum, Mohammad Mamun Alam, K.M. Main Uddin, Md Zakiul Hassan, Mustafizur Rahman, Doli Goswami, W. Abdullah Brooks   +11 more
openalex   +1 more source

Innate Immune Evasion by Human Respiratory RNA Viruses

Journal of Innate Immunity, 2019
The impact of respiratory virus infections on the health of children and adults can be very significant. Yet, in contrast to most other childhood infections as well as other viral and bacterial diseases, prophylactic vaccines or effective antiviral ...
M. Kikkert
semanticscholar   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Nature Communications, 2019
Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al.
Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach   +14 more
doaj   +1 more source

Influenza and the implications of a pandemic for Malta [PDF]

, 2005
An influenza pandemic is inevitable and recent reports from Southeast Asia on avian influenza viruses infecting humans have served to fuel worries that a new pandemic is near.
Farrugia, Ryan, Melillo Fenech, Tanya, Spiteri, Gianfranco   +2 more
core  

Other Community Respiratory Viruses

Clinics in Chest Medicine, 2017
Polymerase chain reaction-based diagnosis has become the standard for viral pneumonia and other respiratory tract infections. Expansion of respiratory viral panels (RVPs) outside of influenza and, possibly, respiratory syncytial virus has led to the ability to diagnose viral infections for which no approved specific antiviral treatment exists.
openaire   +2 more sources

Burden of influenza, respiratory syncytial virus, and other respiratory viruses and the completeness of respiratory viral identification among respiratory inpatients, Canada, 2003‐2014

Influenza and Other Respiratory Viruses, 2017
A regression‐based study design has commonly been used to estimate the influenza burden; however, these estimates are not timely and many countries lack sufficient virological data.
D. Schanzer, M. Saboui, L. Lee, Andrea Nwosu, C. Bancej   +4 more
semanticscholar   +1 more source