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Influenza viruses – antiviral therapy and resistance
Influenza is a serious and frequently underestimated, but vaccine preventable disease. The adamantane derivates rimantadine and amantadine and the neuraminidase inhibitors zanamivir and oseltamivir are the only antiviral drugs currently approved in ...
Duwe, Susanne
doaj +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Deng, Xutao +15 more
core +1 more source
Acute respiratory disease, including the common cold, influenza-like illness, croup, bronchiolitis, and viral pneumonia, can be caused by a wide variety of viral and non-viral agents. Among the viruses, those with RNA genomes tend to play a more prominent role, particularly among immunologically intact individuals.
Treanor, John, Fleming, Douglas
openaire +3 more sources
Introduction: Inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary.
P Mehrbod +4 more
doaj
World Flu Day 2024 with One Health Approach in Iran
Introduction: The global impact and significance of influenza are profound, from the 1918 Spanish flu pandemic to recent seasonal and avian influenza outbreaks.
Parvaneh Mehrbod1*, Behrokh Farahmand1
doaj +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Numerous studies have investigated vaccine-induced correlates of protection (CoP) against severe acute respiratory syndrome–coronavirus 2 (SARS–CoV-2) infection, but data on infection-induced CoP are limited.
Jianrong Shi +9 more
doaj +1 more source
Background Several studies on gamma-irradiated influenza A virus (γ-Flu) have revealed its superior efficacy for inducing homologous and heterologous virus-specific immunity.
Ailar Sabbaghi +7 more
doaj +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

