Results 61 to 70 of about 297,224 (307)

Prokaryotic Expression of the Influenza A (H5N1) Neuraminidase

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Highly Pathogenic Influenza A(H5N1) viruses cause vast economic losses throughout the world. They may circulate in animals and be able to spread from human to human.
Zahra Latif, Behrokh Farahmand, Maryam Saleh, Zahra Barghi   +3 more
doaj  

Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile

Frontiers in Public Health, 2020
The pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the ...
Andrés E. Castillo, Bárbara Parra, Paz Tapia, Jaime Lagos, Loredana Arata, Alejandra Acevedo, Winston Andrade, Gabriel Leal, Carolina Tambley, Patricia Bustos, Rodrigo Fasce, Jorge Fernández   +11 more
doaj   +1 more source

Human Respiratory Viruses

, 2008
Viruses are the leading causes of acute lower respiratory-tract infection in infancy. Respiratory syncytial virus (RSV) is the most common pathogen, with hMPV, PIV-3, influenza viruses, and rhinoviruses accounting for the majority of the remainder of acute viral respiratory infections.
openaire   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Monitoring viral evolution and epidemiological characteristics of SARS-CoV-2 during 2022–2023 using Integrated Genomic Surveillance

Communications Medicine
Background The continued emergence of SARS-CoV-2 variants with increased transmissibility and immunoevasive properties highlights the necessity to complement genomic surveillance with epidemiological data and laboratory-based assessment of viral ...
Christin Mache, Romy Kerber, Jessica Schulze, Marie Lataretu, Susan Abunijela, Yusra Seyam, Sofia Paraskevopoulou, Djin-Ye Oh, Maximilian Arlt, Aleksandar Radonić, Somayyeh Sedaghatjoo, Matthias Budt, Ann-Sophie Lehfeld, Felix Hartkopf, Ralf Dürrwald, Torsten Semmler, Walter Haas, Stephan Fuchs, Stefan Kröger, Thorsten Wolff, Integrated Molecular Surveillance for SARS-CoV-2 (IMSSC2) Laboratory Network   +20 more
doaj   +1 more source

In vitro anti-influenza assessment of anionic compounds ascorbate, acetate and citrate

Virology Journal, 2022
Background Influenza A virus (IAV) infection remains a serious public health threat. Due to drug resistance and side effects of the conventional antiviral drugs, repurposing the available natural compounds with high tolerability and fewer side effects ...
Hadiseh Shokouhi Targhi, Parvaneh Mehrbod, Fatemeh Fotouhi, Mehriar Amininasab   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]

, 2008
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Leberre, Véronique, LE BERRE, Véronique, Baranowski, Eric, François, Jean Marie, Deplanche, Martine, Trouilh, Lidwine   +5 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses [PDF]

, 2012
Swine have often been considered as a mixing vessel for different influenza strains. In order to assess their role in more detail, we undertook a retrospective sequencing study to detect and characterize the reassortants present in European swine and to ...
Pybus, OG, McCauley, J. W., Brown, I. H., Kellam, P., Leigh Brown, AJ, Lycett, S., Baillie, G., Baillie, G, Coulter, E, Brown, IH, Wood, JL, Lycett, S. J., Lycett, SJ, Coulter, E., McCauley, JW, Leigh Brown, A., Wood, J. L. N., Pybus, Oliver G., Bhatt, S., Kellam, P, N Wood, J., ?, ?, Wood, JLN, Pybus, Oliver, Brown Leigh, AJ, Bhatt, S, Brown, AJ Leigh, Brown, A. J. Leigh, Pybus, O. G., Brown, I., McCauley, J.   +30 more
core   +1 more source