Results 71 to 80 of about 1,320,014 (285)

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

In‐Hospital Mortality and Severe Respiratory and Renal Outcomes—A Territory‐Wide Comparison Between RSV and Influenza [PDF]

Introduction: Respiratory syncytial virus (RSV) and influenza virus are important respiratory viruses. Although RSV vaccines have been developed and recommended for patients aged ≥ 60, there is limited data on the clinical impact among the non-elderly ...
Yap, Desmond Yat Hin, Tsui, Chung Ki, To, Kelvin Kai Wang, Leung, Isaac Sze Him, Lam, David Chi Leung, Kwok, Wang Chun, Ho, James Chung Man, Ip, Mary Sau Man   +7 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Monthly Dynamics of Cases of Laryngotracheitis and Recurrent Laryngotracheitis in Children and their Relation to Respiratory Viruses

, 2014
Introduction. One of the most common syndromes in pediatrics is stenotic laryngotracheitis (SLT), in which genesis has a leading role in viruses, and is also characterized by certain seasonal rhythms.
Stanislavchuk L.
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Antiviral susceptibility of SARS-CoV-2 and influenza viruses from 3 co-infected pediatric patients

International Journal of Infectious Diseases
In Japan, influenza activity was low throughout the COVID-19 pandemic until the 2022-23 season, when the first influenza outbreak occurred since the 2020-21 season.
Emi Takashita, Masataka Ichikawa, Seiichiro Fujisaki, Hiroko Morita, Shiho Nagata, Hideka Miura, Shinji Watanabe, Hideki Hasegawa, Yoshihiro Kawaoka   +8 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Biochemical analysis of packing and assembling heptad repeat motifs in the coronavirus spike protein trimer

mBio
During a coronavirus infection, the spike protein undergoes sequential structural transitions triggered by its receptor and the host protease at the interface between the virus and cell membranes, thereby mediating membrane fusion. After receptor binding,
Jun Kobayashi, Kazuhiko Kanou, Hiyori Okura, Tahmina MST Akter, Shuetsu Fukushi, Shutoku Matsuyama   +5 more
doaj   +1 more source

Respiratory Viruses

, 2018
This article is an overview of the most clinically important respiratory viruses including the recently emerged highly pathogenic coronaviruses and other viruses that are transmitted via the respiratory tract. In this article, we highlight a description of the agent, its life cycle, epidemiology, pathogenesis, clinical features, diagnosis and ...
Weston, Stuart, Frieman, Matthew B.
openaire   +1 more source

Role of Respiratory Viruses in Severe Acute Respiratory Failure

Respiratory viruses are widespread in the community, affecting both the upper and lower respiratory tract. This review provides an updated synthesis of the epidemiology, pathophysiology, clinical impact, and management of severe respiratory viral ...
Mokrani, David, Timsit, Jean-François, Jean-François Timsit, David Mokrani   +3 more
core   +1 more source