Results 41 to 50 of about 297,367 (306)

Prevalence of circulating antibodies against hemagglutinin of influenza viruses in epidemic season 2021/2022 in Poland

Acta Biochimica Polonica
The aim of the study was to determine the level of anti-hemagglutinin antibodies in the serum of patients during the 2021/2022 epidemic season in Poland.
Katarzyna Kondratiuk, Ewelina Hallmann, Karol Szymański, Katarzyna Łuniewska, Anna Poznańska, Lidia B. Brydak   +5 more
doaj   +1 more source

Analysis of Viral and Host Factors on Immunogenicity of 2018, 2019, and 2020 Southern Hemisphere Seasonal Trivalent Inactivated Influenza Vaccine in Adults in Brazil

Viruses, 2022
Annual vaccination against influenza is the best tool to prevent deaths and hospitalizations. Regular updates of trivalent inactivated influenza vaccines (TIV) are necessary due to high mutation rates in influenza viruses.
Artur Capão, Maria L. Aguiar-Oliveira, Braulia C. Caetano, Thayssa K. Neves, Paola C. Resende, Walquiria A. F. Almeida, Milene D. Miranda, Olindo A. Martins-Filho, David Brown, Marilda M. Siqueira, Cristiana C. Garcia   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Evaluation and adaptation of molecular approaches for detection and characterization of viruses of the respiratory tract [PDF]

, 2011
This study was designed for the development of novel methods for isothermal amplification of nucleic acids using phi29 and Bst DNA polymerases in the detection and characterization of pathogenic viruses of the respiratory tract.
Kabir, Md. Shahidul
core   +1 more source

Optimized production of a truncated form of the recombinant neuraminidase of influenza virus in Escherichia coli as host with suitable functional activity

Microbial Cell Factories
Background To discover effective drugs for treating Influenza (a disease with high annual mortality), large amounts of recombinant neuraminidase (NA) with suitable catalytic activity are needed. However, the functional activity of the full-length form of
Fatemeh Sadat Shariati, Fatemeh Fotouhi, Behrokh Farahmand, Zahra Barghi, Kayhan Azadmanesh   +4 more
doaj   +1 more source

Increase of Synergistic Secondary Antiviral Mutations in the Evolution of A(H1N1)pdm09 Influenza Virus Neuraminidases

Viruses
The unexpected emergence of oseltamivir-resistant A(H1N1) viruses in 2008 was facilitated in part by the establishment of permissive secondary neuraminidase (NA) substitutions that compensated for the fitness loss due to the NA-H275Y resistance ...
Susanne C. Duwe, Jeanette Milde, Alla Heider, Marianne Wedde, Brunhilde Schweiger, Ralf Dürrwald   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives [PDF]

, 2020
The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. Besides, retrospective studies, improved lab-based detection methods and the intensified search for new viruses
Antalis, E., Skevaki, C., ESCMID Study Group for Respiratory Viruses (ESGREV), Tsiodras, S., Fragkou, P.C., Rath, B.A., Nelson, P.P.   +6 more
core  

Occurrence of Circulating Antibodies against the Hemagglutinins of Influenza Viruses in the 2022/2023 Epidemic Season in Poland

Viruses
The aim of this study was to determine the level of anti-hemagglutinin antibodies in blood sera collected from patients during the 2022/2023 epidemic season in Poland. A total of 700 sera samples from patients across the country were tested.
Katarzyna Kondratiuk, Anna Poznańska, Karol Szymański, Emilia Czajkowska, Bartosz Mańkowski, Lidia B. Brydak   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source