Results 91 to 100 of about 10,606,337 (342)

On the automaticity of response inhibition in individuals with alcoholism [PDF]

open access: yesJournal of Behavior Therapy and Experimental Psychiatry, 2016
Response inhibition is usually considered a hallmark of executive control. However, recent work indicates that stop performance can become associatively mediated ('automatic') over practice. This study investigated automatic response inhibition in sober and recently detoxified individuals with alcoholism..We administered to forty recently detoxified ...
Noël, Xavier   +5 more
openaire   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Tumor Mutational Burden and Response Rate to PD-1 Inhibition.

open access: yesNew England Journal of Medicine, 2017
In a survey of the spectrum of mutational burdens in 27 types of cancers, there was a correlation between an increased mutational burden and the response to checkpoint inhibition of PD-1 and PD-L1.
M. Yarchoan   +2 more
semanticscholar   +1 more source

Modeling response inhibition

open access: yes, 2017
Presentation on models of response inhibition for the course ‘Cognitive control’ of the MSc program Cognitive Neuroscience at Radboud University. Topics addressed include background on response inhibition, the independent race model of the stop-signal task, and sequential sampling models of response inhibition.
openaire   +1 more source

Meaningful inhibition: Exploring the role of meaning and modality in response inhibition [PDF]

open access: yesNeuroImage, 2018
We frequently guide our decisions about when and how to act based on the meanings of perceptual inputs: we might avoid treading on a flower, but not on a leaf. However, most research on response inhibition has used simple perceptual stimuli devoid of meaning.
Gonzalez Alam, Tirso Rene Del Jesus   +3 more
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Inhibitory control processes and the strategies that support them during hand and eye movements

open access: yesFrontiers in Psychology, 2016
Background and Aims: Adaptive behavior depends on the ability to voluntarily suppress context-inappropriate behaviors, a process referred to as response inhibition. Stop Signal tests (SSTs) are the most frequently studied paradigm used to assess response
Lauren Michelle Schmitt   +3 more
doaj   +1 more source

It's not too late: the onset of the frontocentral P3 indexes successful response inhibition in the stop-signal paradigm.

open access: yesPsychophysiology, 2015
The frontocentral P3 event-related potential has been proposed as a neural marker of response inhibition. However, this association is disputed: some argue that P3 latency is too late relative to the timing of action stopping (stop-signal reaction time ...
J. Wessel, A. Aron
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Response inhibition deficits in externalizing child psychiatric disorders: An ERP-study with the Stop-task

open access: yesBehavioral and Brain Functions, 2005
Background Evidence from behavioural studies suggests that impaired motor response inhibition may be common to several externalizing child psychiatric disorders, although it has been proposed to be the core-deficit in AD/HD. Since similar overt behaviour
Heinrich Hartmut   +4 more
doaj   +1 more source

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