Inhibiting responses to difficult choices. [PDF]
The stop-signal paradigm is a widely used procedure to study response inhibition. It consists of a 2-choice response-time task (a "go" task) that is occasionally interrupted by a stop signal instructing participants to withhold their responses. The paradigm owes its popularity to the underlying race model that enables estimation of the otherwise ...
Matzke, D. +3 more
openaire +3 more sources
Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition [PDF]
EZH2 inhibitors have gained great interest for their use as anti-cancer therapeutics. However, most research has focused on EZH2 mutant cancers and recently adverse effects of EZH2 inactivation have come to light.
Bounova, Gergana +6 more
core +1 more source
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A. +6 more
core +1 more source
Recent findings in monkeys suggest that action selection is based on a competition between various action options that are automatically planned by the motor system.
Fausto eCaruana +7 more
doaj +1 more source
Optimal designs for enzyme inhibition kinetic models [PDF]
In this paper we present a new method for determining optimal designs for enzyme inhibition kinetic models, which are used to model the influence of the concentration of a substrate and an inhibition on the velocity of a reaction.
Dette, Holger +3 more
core +2 more sources
Previous research provides evidence for a dissociable embodied route to spatial perspective-taking that is under strategic control. The present experiment investigated further the influence of strategy on spatial perspective-taking by assessing whether ...
Mark eGardner +3 more
doaj +1 more source
A Comparison of the Effects of “Computerized Cognitive Rehabilitation Game of Attention and Memory” and “Practical Games of Attention” on Sustained Attention, Response Inhibition, Reading Speed, and Accuracy of Reading in Students with Specific Learning Disability of Dyslexia [PDF]
The present study aimed to compare the effects of “computerized cognitive rehabilitation game of attention and memory (ARAM)” and “practical games of attention” on sustained attention, response inhibition, reading speed, and accuracy of reading in ...
Mohammad Drikvand +2 more
doaj +1 more source
AKT activation controls cell survival in response to HDAC6 inhibition. [PDF]
HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor.
Aboagye, EO +3 more
core +1 more source
The purpose of this study was to examine whether the beneficial effects of behavioral parent training (BPT), as an indirect type of psychosocial treatment, are extended to cognitive manifestations beyond behavioral symptoms of attention-deficit ...
Akiko Yao +8 more
doaj +1 more source
The practice of going helps children to stop:The importance of context monitoring in inhibitory control [PDF]
How do we stop ourselves during ongoing action? Recent work implies that stopping per se is easy given sufficient monitoring of contextual cues signaling the need to change action.
Chatham, Christopher H +2 more
core +1 more source

