Results 51 to 60 of about 1,613,093 (146)
Background: Amphetamines increase dopamine levels in mid-brain regions which, in turn, impact top-down executive function. Repeated exposure is linked to substance use disorders.
Antoinette Poulton +4 more
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Disinhibition is present in various maladaptive behaviours, including substance use disorders. Most previous research has assumed that disinhibition is a psychological construct that is relatively stable within individuals.
Andrew eJones +4 more
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Being able to stop (or inhibit) an action rapidly as in a stop-signal task is an essential human ability. Previous studies showed that when a pre-stimulus cue warned of the possible need to stop a response in an upcoming trial, participants’ response ...
Benjamin eXu +7 more
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Background and aim: Cerebral areas related to executive functions, during adolescence and early youth encounter with structural and functional changes and fluctuations that expose adolescents to many problems including drug abuse.
Abdollah Salmani +2 more
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Presentation on models of response inhibition for the course ‘Cognitive control’ of the MSc program Cognitive Neuroscience at Radboud University. Topics addressed include background on response inhibition, the independent race model of the stop-signal task, and sequential sampling models of response inhibition.
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Myopic decisions under negative emotions correlate with altered time perception
Previous studies have obtained inconsistent findings about emotional influence on inter-temporal choice. In the present study, we first examined the effect of temporary emotional priming induced by affective pictures in a trial-to-trial paradigm on inter-
Shuchen eGuan +3 more
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Inhibitory Control and Fall Prevention: Why Stopping Matters
David A. E. Bolton, James K. Richardson
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Go/no-go tasks are widely used to index cognitive control. This construct has been linked to white matter microstructure in a circuit connecting the right inferior frontal gyrus (IFG), subthalamic nucleus (STN), and pre-supplementary motor area. However,
Kendra E. Hinton +10 more
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HSP90 inhibition without heat shock response [PDF]
In this issue of Blood, Bhatia and colleagues describe a heat shock protein 90 (HSP90) C-terminal dimerization inhibitor with mechanistic differences that distinguish it from other clinically unsuccessful N-terminal ATPase binding compounds.1 Can graveyard raiding of an old therapeutic target with a new strategy bring long awaited success?
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IntroductionLower sensitivity (LS) to acute alcohol promotes hazardous alcohol use, increasing risk for alcohol use disorder (AUD). Compared to peers with high sensitivity (HS), LS individuals exhibit amplified responses to alcohol cues and difficulty ...
Roberto U. Cofresí +7 more
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