Results 101 to 110 of about 2,569,579 (302)

Symmetrization and enhancement of the continuous Morlet transform

, 2012
The forward and inverse wavelet transform using the continuous Morlet basis may be symmetrized by using an appropriate normalization factor. The loss of response due to wavelet truncation is addressed through a renormalization of the wavelet based on ...
Fligge M., Frick P., Johnson R. W., Kaiser G., Kaiser G., Piscaronoft P., Press W. H., ROBERT W. JOHNSON, Sivia D. S.   +8 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Enhanced many-body effects in the excitation spectrum of a weakly-interacting rotating Bose-Einstein condensate

, 2018
The excitation spectrum of a highly-condensed two-dimensional trapped Bose-Einstein condensate (BEC) is investigated within the rotating frame of reference. The rotation is used to transfer high-lying excited states to the low-energy spectrum of the BEC.
Alon, Ofir E., Beinke, Raphael, Cederbaum, Lorenz S.   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Spectral analysis of layered sites using shaking table tests.

PLoS ONE, 2019
The dynamic response analysis of horizontal and inclined layered sites using large-scale shaking table tests in various directions, including the dip direction, strike, vertical direction, slope direction and direction perpendicular to the interface of ...
Gang Fan, Jianjing Zhang, Jinbiao Wu, Kongming Yan   +3 more
doaj   +1 more source

Multivariate statistical analysis for damage and delamination in composite structures [PDF]

, 2013
The article is devoted to the analysis of the vibration response of composite laminates .Our aim is to develop a method for analysis of the vibration response of structures made of composites which will also be used to develop a vibration-based health ...
Garcia, David, Trendafilova, Irina
core  

Parity forbidden excitations of Sr2CuO2Cl2 revealed by optical third-harmonic spectroscopy

, 2001
We present the first study of nonlinear optical third harmonic generation in the strongly correlated charge-transfer insulator Sr2CuO2Cl2. For fundamental excitation in the near-infrared, the THG spectrum reveals a strongly resonant response for photon ...
A. B. Schumacher, A. Schülzgen, C. M. Varma, D. S. Chemla, D. S. Chemla, D. Salamon, E. Hanamura, F. C. Zhang, G. P. Zhang, H. Kishida, H. S. Choi, J. P. Hermann, J. S. Dodge, L. L. Miller, L. L. Miller, M. A. Carnahan, M. A. Kastner, M. E. Simón, M. Grilli, M. Z. Hasan, P. D. Maker, P. Kuiper, P. W. Anderson, R. A. Kaindl, R. Liu, R. Lövenich, R. W. Boyd   +26 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source