Results 101 to 110 of about 2,257,568 (316)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

THE INFLUENCES OF NATURAL GAS IMPURITIES TO THE SURFACE TENSION OF BLENDED PIPERAZINE-N-METHYLDIETHANOLAMINE (MDEA) SOLUTION [PDF]

open access: yes, 2008
This study focuses on the effect of impurities in the natural gas stream on the characteristic of surface tension in the blended piperazine and MDEA solution.
Ismail, Ahmad Fauzi, Ratman, Iwan
core  

Optimization of Deep Eutectic Solvent Extraction Process of Polysaccharides from Dendrobium officinale

open access: yesShipin gongye ke-ji
In order to increase the comprehensive utilization of Dendrobium officinale, a green and efficient method for extracting of Dendrobium officinale polysaccharides (DOPs) was established.
Simin FENG   +5 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Optimization of shot peening parameters by response surface methodology

open access: yes, 2016
In this study, the shot peening parameters which directly influence the arc height of the Almen strip and its characteristics are optimized within the context of Almen intensity, surface roughness and surface hardness via response surface methodology ...
Unal, Okan
core   +1 more source

European climate response to tropical volcanic eruptions over the last half millennium [PDF]

open access: yes, 2007
We analyse the winter and summer climatic signal following 15 major tropical volcanic eruptions over the last half millennium based on multi-proxy reconstructions for Europe. During the first and second post-eruption years we find significant continental
Tett, S. F. B.   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Response of segmented bored transit tunnels to surface blast

open access: yes, 2015
Increasing threat of terrorism highlights the importance of enhancing the resilience of underground tunnels to all hazards. This paper develops, applies and compares the Arbitrary Lagrangian Eulerian (ALE) and Smooth Particle Hydrodynamics (SPH ...
Gallage, Chaminda   +2 more
core   +1 more source

Grinding surface roughness measurement based on the co-occurrence matrix of speckle pattern texture [PDF]

open access: yes, 2006
Surface speckle pattern intensity distribution resulting from laser light scattering from a rough surface contains various information about the surface geometrical and physical properties.A surface roughness measurement technique based on the texture ...
Gledhill, Duke   +4 more
core   +1 more source

Strength and durability of concrete with bentonite clay and quarry dust

open access: yesFrontiers in Materials
The research object is concrete with supplementary cementitious materials (SCMs) such as bentonite clay and quarry dust. The impact of incorporating these SCMs on fresh concrete properties, compressive, flexural, and split tensile strengths, and acid ...
Muhammad Umar   +7 more
doaj   +1 more source

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