Results 121 to 130 of about 1,313,206 (306)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Performance Prediction and Optimization of Nanofluid-Based PV/T Using Numerical Simulation and Response Surface Methodology

Nanomaterials
A numerical investigation was carried out in ANSYS Fluent® on a photovoltaic/thermal (PV/T) system with MXene/water nanofluid as heat transfer fluid (HTF).
Sreehari Sreekumar, Supriya Chakrabarti, Neil Hewitt, Jayanta Deb Mondol, Nikhilkumar Shah   +4 more
doaj   +1 more source

Forced response prediction for industrial gas turbine blades [PDF]

, 2006
A highly efficient aeromechanical forced response system is developed for predicting resonant forced vibration of turbomachinery blades with the capabilities of fully 3-D non-linear unsteady aerodynamics, 3-D finite element modal analysis and blade root ...
Moffatt, Stuart
core  

A New Adaptive Higher Order Response Surface Method

, 2011
Response surface method has won numerous concerns in the reliability analysis of structure due to its simplicity and practicability, especially quadratic response surface taking no account of cross terms is most widely used.
Zheng Liang Li, Wen Liang Fan, Feng Han
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

An expression for land surface water storage monitoring using a two-formation geological weighing lysimeter

, 2007
Field studies have demonstrated that ground surface rainfall accumulation can be detected at depth by synchronous increases in static confined groundwater pore pressures.
Bardsley, W. Earl, Campbell, David I.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Therapeutic Effect of Calcipotriol Pickering Nanoemulsions Prepared by Exopolysaccharides Produced by Bacillus halotolerans FYS Strain on Psoriasis

International Journal of Nanomedicine, 2020
Yuzhen Wang,1 Hong Li,2 Fakun Dong,3 Fang Yan,3 Min Cheng,4 Wanzhong Li,3 Qi Chang,3 Tianzi Song,3 Aoying Liu,3 Bo Song3 1Medical Imaging Specialty, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2Basic Medical School ...
Wang Y, Li H, Dong F, Yan F, Cheng M, Li W, Chang Q, Song T, Liu A, Song B   +9 more
doaj  

Optimization of shot peening parameters by response surface methodology

, 2016
In this study, the shot peening parameters which directly influence the arc height of the Almen strip and its characteristics are optimized within the context of Almen intensity, surface roughness and surface hardness via response surface methodology ...
Unal, Okan
core   +1 more source