Results 131 to 140 of about 1,313,206 (306)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Study on the freeze-thaw effect on concrete arch dam using an improved response surface method. [PDF]
Cai Q, Yang M, Yang J.
europepmc +1 more source
Stochastic Trust Region Response Surface Convergent Method for generally-distributed response surface [PDF]
Kuo-Hao Chang, Hong Wan
openaire +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Optimum Design of Structure by Response Surface Method
本研究將應用回應表面法於結構的尺寸最佳化設計,並且使用縮小設計空間等技 巧快速地求出結構之迴歸模型。本文將會採用逐步迴歸的分析方式來有效地確保 其設計變數和回應值之間的關聯性。利用準確度較高的回應表面函數將不但可以 節省計算機運算的時間,並且有助於設計者對於系統模型的判斷和分析。The objective of this study is to minimize the structural weight subject to the specific constrains by response ...
教育部;逢甲大學;工研院系統與航太科技發展中心; 中國航空太空學會;國科會工程處工程推展中心;漢翔航空工業股份有限公司; 中華民用航空學會;成功大學航太中心;中山科學研究院 +2 more
core
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
A Parallel Response Surface Method
[[abstract]]In this thesis an optimization problems for finding multiple extremes in computer experiments (Sacks et al., 1989, and Koehler and Owen, 1996) are considered. To solve this kind of problems, a novel method is proposed.
Liu, Kuang-Yen, 劉光晏
core
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Load Monitoring Using Surface Response to Excitation Method
Surface response to excitation (SuRE) method is a low-cost alternative to the electromechanical impedance method developed for the structural health monitoring (SHM) applications. This method uses one piezoelectric transducer to excite the surface of a structure with a sweep sine wave.
Tashakori, S. +6 more
openaire +3 more sources

