Results 41 to 50 of about 1,264,545 (307)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Response Surface Stochastic Finite Element Method of Composite Structure
Response Surface Method (RSM) has been applied to structural reliability problems successfully in many areas. Finite Element Method (FEM) is one of the most widely used computational methods, which permit the analysis and design of large-scale ...
Cai Deyong, Liu Fujun
doaj +1 more source
Optimization of Pigment Extraction from Red Beet [PDF]
Introduction The first quality attribute about food evaluated by consumer is visual characteristics. The apparent attributes of a product include its shape, color, packaging, size, and uniformity.
Mahshad Lavarsetagh +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Response Surface Method for Material Uncertainty Quantification of Infrastructures
Recently, probabilistic simulations became an inseparable part of risk analysis. Managers and stakeholders prefer to make their decision knowing the existing uncertainties in the system.
Mohammad Amin Hariri-Ardebili +2 more
doaj +1 more source
Optimization of bioactive compound extraction from tobacco stem (Nicotiana tabacum L.) [PDF]
Tobacco stem represents an underutilized agricultural by-product rich in bioactive secondary metabolites such as phenolics, flavonoids, alkaloids, terpenoids, and saponins.
Budiati Titik +4 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gaussian Process-Based Response Surface Method for Slope Reliability Analysis
A new response surface method (RSM) for slope reliability analysis was proposed based on Gaussian process (GP) machine learning technology. The method involves the approximation of limit state function by the trained GP model and estimation of failure ...
Bin Hu +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This study explores the use of a statistical model to build a design space for freeze-drying two formulations with ibuprofen. A 2 × 3 factorial experimental design was used to evaluate independent variables (filling volume and annealing time) and ...
Preskar Maja +3 more
doaj +1 more source

