Results 41 to 50 of about 3,378,607 (346)

Coupled ocean–atmosphere interactions between the Madden–Julian oscillation and synoptic-scale variability over the warm pool [PDF]

, 2005
A principal component analysis of the combined fields of sea surface temperature (SST) and surface zonal and meridional wind reveals the dominant mode of intraseasonal (30-70-day) co-variability during northern winter in the tropical Eastern Hemisphere ...
Batstone, Crispian P., Matthews, Adrian J., Stevens, David P.   +2 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Comparison between Newton and response-surface methods [PDF]

Structural and Multidisciplinary Optimization, 2005
ISSN:1615 ...
Kress, G.R., Ermanni, P.
openaire   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Investigation of design space for freeze-drying injectable ibuprofen using response surface methodology

Acta Pharmaceutica, 2021
This study explores the use of a statistical model to build a design space for freeze-drying two formulations with ibuprofen. A 2 × 3 factorial experimental design was used to evaluate independent variables (filling volume and annealing time) and ...
Preskar Maja, Videc Danijel, Vrečer Franc, Gašperlin Mirjana   +3 more
doaj   +1 more source

Optimasi Sintesis Ligan Diheksilditiofosfat (DHDTP) Menggunakan Response Surface Method (RSM)

Pendipa, 2021
Dihexyldithiophosphate (DHDTP) ligand is one of the homologues of dialkyldithiophosphate which is potentially better as an extractant in solvent extraction.
Diana Hendrati, Yulia Mardhotillah, Anni Anggraeni, M. Lutfi Firdaus, Santhy Wyantuti   +4 more
doaj   +1 more source

Comparison of Stochastic Methods for the Variability Assessment of Technology Parameters [PDF]

, 2011
This paper provides and compares two alternative solutions for the simulation of cables and interconnects with the inclusion of the effects of parameter uncertainties, namely the Polynomial Chaos (PC) method and the Response Surface Modeling (RSM).
Bellan, Debusschere, Devore, F. G. Canavero, Ghanen, Gorissen, I. S. Stievano, M. Fontana, Manfredi, Manfredi, Morris, Myers, P. Manfredi, Papoulis, Paul, Shiran, Stievano, Strunz, Wiener, Xiu, Zhang, Zou   +21 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Pseudo-Fermi surface and phonon softening in sodium with a stepwise electron distribution

, 2019
The absorption of light by a metal disturbs the electron distribution around the Fermi surface. Here, we calculate the phonon dispersion relations of free-electron-like metal, bcc sodium, with a stepwise electron distribution function by using a model ...
Kobayashi, Daigo, Ono, Shota
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source