Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation [PDF]
Background: Drug-eluting stents reduce the incidence of in-stent restenosis, but they result in delayed arterial healing and are associated with a chronic inflammatory response and hypersensitivity reactions. Identifying novel interventions to enhance
Baker, Andrew H.+13 more
core +1 more source
Abstract Background Elderly patients with ST‐elevation myocardial infarction (STEMI) who undergo percutaneous coronary intervention (PCI) are usually excluded from major trials. Hyopthesis This study sought to assess 1‐year clinical outcomes following PCI with a drug‐eluting stent in patients older than 80 years old with STEMI.
Majdi Saada+11 more
wiley +1 more source
Hyperhomocysteinemia and recurrent carotid stenosis
Background Hyperhomocysteinemia has been identified as a potential risk for atherosclerotic disease in epidemiologic studies. This study investigates the impact of elevated serum homocysteine on restenosis after carotid endarterectomy (CEA). Methods In a
Liewald Florian+3 more
doaj +1 more source
Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy. [PDF]
BACKGROUND: The anatomy of carotid stenosis may influence the outcome of endovascular treatment or carotid endarterectomy. Whether anatomy favors one treatment over the other in terms of safety or efficacy has not been investigated in randomized trials.
Angus-Leppan, H.+154 more
core +2 more sources
Cryoplasty for Arterial Restenosis [PDF]
A prospective follow-up study of patients with arterial restenosis undergoing cryoplasty.Between May 2004 and June 2005, 10 patients with restenosis following ilio-femoral endovascular treatment underwent twelve cryoplasty procedures. All patients had had at least one previous episode of stenosis treated by conventional endovascular methods and had ...
Jai V. Patel+6 more
openaire +2 more sources
A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L.+4 more
core +2 more sources
In Stent Restenosis Predictors after Carotid Artery Stenting
Purpose. The long-term efficacy of carotid artery stenting is debated. Predictors of stent restenosis are not fully investigated. Our aim was to assess the incidence of long term restenosis after CAS and to identify some predictors of restenosis. Methods.
Mirco Cosottini+7 more
doaj +1 more source
Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating [PDF]
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21.
A Arsiwala+62 more
core +1 more source
Non-intrusive and semi-intrusive uncertainty quantification of a multiscale in-stent restenosis model [PDF]
Uncertainty estimations are presented of the response of a multiscale in-stent restenosis model, as obtained by both non-intrusive and semi-intrusive uncertainty quantification. The in-stent restenosis model is a fully coupled multiscale simulation of post-stenting tissue growth, in which the most costly submodel is the blood flow simulation. Surrogate
arxiv +1 more source
Paclitaxel eluting stents versus bare metal stents restenosis
Introduction: The restenosis of the paclitaxel-eluting stents used in Cuba has not been studied. Objective: To evaluate the restenosis of paclitaxel-eluting stents and conventional stents.
Ronald Aroche Aportela+5 more
doaj