Restless legs syndrome (RLS) is one of the most common neurological disorders. It describes an irresistible urge to move the legs, mostly manifested in the evening and at night, which can lead to severe sleep disturbance.
C. Trenkwalder +7 more
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Restless Legs Syndrome Presenting as an Acute Exacerbation of Multiple Sclerosis [PDF]
Restless legs syndrome is common in patients with multiple sclerosis but has not been reported as occurring due to an acute, inflammatory, demyelinating attack. Restless legs syndrome is known to be related to low brain iron levels.
Bernheimer, James H.
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Iron for the treatment of restless legs syndrome.
BACKGROUND Restless legs syndrome (RLS) is a common neurologic disorder that is associated with peripheral iron deficiency in a subgroup of patients. It is unclear whether iron therapy is effective treatment for RLS. OBJECTIVES To evaluate the efficacy
L. Trotti, L. Becker
semanticscholar +1 more source
Restless Legs Syndrome Associated With Fexofenadine Use: A Case Report [PDF]
Flowchart of possible fexofenadine‐induced RLS pathophysiology. ABSTRACT Restless legs syndrome (RLS) is a neurological sensorimotor disorder characterized by an irresistible urge to move the legs, typically worsening at night and leading to sleep disturbance.
Albeshry A.
europepmc +2 more sources
New Insights into the Neurobiology of Restless Legs Syndrome
Restless legs syndrome (RLS) is a common sensorimotor disorder, whose basic components include a sensory experience, akathisia, and a sleep-related motor sign, periodic leg movements during sleep (PLMS), both associated with an enhancement of the ...
S. Ferré +3 more
semanticscholar +1 more source
Restless Legs Syndrome Secondary to Iron Deficiency Anaemia: A Case Report. [PDF]
Gul A, Khan Z.
europepmc +3 more sources
Sleep Disorders and Genes [PDF]
Versão preprintThe sleep-wake cycle is a neurobiological phenomenon that shows intervals of activity alternating with restfulness that appears with a periodicity approximating the 24h day-night cycle.
Amici +101 more
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Restless Legs Syndrome: From Pathophysiology to Clinical Diagnosis and Management
Restless legs syndrome (RLS), a common neurological sensorimotor disorder in western countries, has gained more and more attention in Asian countries. The prevalence of RLS is higher in older people and females.
Shiyi Guo +9 more
semanticscholar +1 more source
The Sleep Or Mood Novel Adjunctive therapy (SOMNA) trial: a study protocol for a randomised controlled trial evaluating an internet-delivered cognitive behavioural therapy program for insomnia on outcomes of standard treatment for depression in men [PDF]
BACKGROUND: Insomnia is a significant risk factor for depression onset, can result in more disabling depressive illness, and is a common residual symptom following treatment cessation that can increase the risk of relapse.
Christensen, Helen M. +7 more
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Restless legs syndrome and ferritin levels in older adults with dementia: a cross-sectional study [PDF]
. In cases of dementia or major neurocognitive disorder, restless legs syndrome has not been extensively studied because the diagnosis relies on clinical assessments and self-reports from patients. Objective: The aim of this study was to investigate the
Érica Dayanne Meireles Leite +5 more
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