Results 91 to 100 of about 830,111 (315)

ROS homeostasis and cell wall biosynthesis pathway are involved in female inflorescence development of birch (Betula platyphylla)

BMC Plant Biology
Background Female inflorescence development from megasporogenesis to gametogenesis, and mature female gametophyte (FG), is a complex and important event in plant sexual reproduction. However, how this essential developmental process is regulated in birch
Mengjie Cai, Kehao Zeng, Lanlan Li, Jiayuan Shi, Bello Hassan Jakada, Xue Zhang, Pu Wang, Haonan Zhu, Jing Jiang, Xingguo Lan   +9 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

South African grassland ecology and its restoration

, 2013
The aim of this study is to investigate how human related disturbances affect mesic grasslands. I identified what was lost from the system after a disturbance and what biological constraints ecologists and managers will face when approaching their ...
Zaloumis, Nicholas Paul
core  

Restoring the Regulated: The EU's Nature Restoration Law

Journal of Environmental Law
Abstract To halt the decline of the natural environment, attention is increasingly directed towards nature restoration. A recent example of this is the EU’s Nature Restoration Law (NRL). This article presents an assessment of the NRL, arguing that the NRL is ambitious but that this ambition comes with a risk of it becoming a performative
Emma Lees, Ole W Pedersen
openaire   +2 more sources

Restoration of Anchisaurus. [PDF]

American Journal of Science, 1893
n ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Assessing acute thermal assays as a rapid screening tool for coral restoration

Scientific Reports
Escalating environmental threats to coral reefs coincides with global advancements in coral restoration programs. To improve long-term efficacy, practitioners must consider incorporating genotypes resilient to ocean warming and disease while maintaining ...
C. N. Klepac, C. G. Petrik, E. Karabelas, J. Owens, E. R. Hall, E. M. Muller   +5 more
doaj   +1 more source

Decoding anthropogenic risk through historical baselines: a conservation prioritization framework for Chinese white dolphin in anthropogenic seascapes

Frontiers in Marine Science
Coastal cetaceans confront intensifying anthropogenic pressures, yet quantifying historical habitat loss remains methodologically challenging in data-scarce regions where shifting baseline syndrome obscures conservation targets.
Liming Yong, Liming Yong, Xixia Lu, Xixia Lu, Qianhui Zeng, Qianhui Zeng, Liyuan Zhao, Liyuan Zhao, Yuke Zhang, Yuke Zhang, Xianyan Wang, Xianyan Wang   +11 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Ecological restoration success : a policy analysis understanding [PDF]

, 2016
This article discusses how ecological restoration success can be understood and evaluated using a policy analysis lens. First, this article details a conceptual tool that helps to develop a more encompassing set of criteria to assess restoration ...
Eckerberg, Katarina, Baker, Susan, Baker, Susan Catherine, Eckerberg, Katarina,, Baker, Susan,   +4 more
core   +1 more source