Results 61 to 70 of about 1,147,765 (344)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Bone Marrow CD133 Stem Cells Ameliorate Visual Dysfunction in Streptozotocin-induced Diabetic Mice with Early Diabetic Retinopathy

open access: yesCell Transplantation, 2018
Diabetic retinopathy (DR), one of the leading causes of vision loss worldwide, is characterized by neurovascular disorders. Emerging evidence has demonstrated retinal neurodegeneration in the early pathogenesis of DR, and no treatment has been developed ...
Liyuan Rong   +9 more
doaj   +1 more source

New Sample of Ancient Art from Kazakh Altay

open access: yesПоволжская археология, 2019
In the paper, for the first time, the results of a laboratory study of a finding representing a fragment of a saddle coat are entered into a scientific circulation. Embroidery was being able to be reconstructed after 18 years since the discovery.
Altynbekov Krym   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Governor’s Award for restoration

open access: yesПроект Байкал, 2023
The Irkutsk Region Governor’s Award for Achievements in Culture and Art 2022 in the category “Works of Architecture, Urban Planning and Park Art” was awarded to the creative team consisting of Alexey Polikarpochkin, Maria Borisova, Lidia Zakharova ...
Лидия Захарова   +1 more
doaj   +1 more source

Residual Dense Network for Image Restoration [PDF]

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence, 2018
Recently, deep convolutional neural network (CNN) has achieved great success for image restoration (IR) and provided hierarchical features at the same time. However, most deep CNN based IR models do not make full use of the hierarchical features from the
Yulun Zhang   +4 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Analysis of Spatial and Temporal Changes in Ecological Quality and Its Drivers in the Baiyangdian Watershed

open access: yesRemote Sensing
As a critical ecological security node in North China, the Baiyangdian Basin underpins regional water resources, biodiversity conservation, and environmental risk mitigation.
Haoyang Wang   +5 more
doaj   +1 more source

Structural and bio-functional assessment of the postaxillary gland in Nidirana pleuraden (Amphibia: Anura: Ranidae)

open access: yesZoological Letters, 2020
Background Owing to their incomplete adaptation to the terrestrial environment, amphibians possess complex cutaneous glandular systems. The skin glands not only regulate water loss and respiratory gas and salt exchange, but are also involved in defense ...
Yuzhou Gong   +4 more
doaj   +1 more source

Habitat restoration is the greatest challenge for population recovery of Hainan gibbons (Nomascus hainanus) [PDF]

open access: hybrid, 2022
Qingqing He   +5 more
openalex   +1 more source

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