Results 41 to 50 of about 395,262 (311)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Using RIVPACS for studies on conservation and biodiversity [PDF]

open access: yes, 2000
Invertebrate conservation relies not only on public support and political will, but also on possessing an adequate understanding of the distribution and ecology of invertebrate species and communities.
Boon, P.J.
core  

Effects of landscape gradients on wetland vegetation communities: information for large-scale restoration [PDF]

open access: yes, 2008
Projects of the scope of the restoration of the Florida Everglades require substantial information regarding ecological mechanisms, and these are often poorly understood. We provide critical base knowledge for Everglades restoration by characterizing the
Kitchens, Wiley M., Zweig, Christa L.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Influence of Lime in Adobe Optimization Against Humidity [PDF]

open access: yesمسکن و محیط روستا, 2018
The importance and the value of historical buildings and sites and even villages which have adobe houses causes that conservators annually schedule restoration plans and programs to protect the buildings from hazards. This is done because conservation of
kaveh Bahramzadeh   +2 more
doaj  

Great Bay Estuary Restoration Compendium [PDF]

open access: yes, 2006
Single species approaches to natural resource conservation and management are now viewed as antiquated and oversimplified for dealing with complex systems.
Burdick, David M.   +3 more
core   +1 more source

Restoring proximal caries lesions conservatively with tunnel restorations

open access: yesClinical, Cosmetic and Investigational Dentistry, 2013
The tunnel restoration has been suggested as a conservative alternative to the conventional box preparation for treating proximal caries. The main advantage of tunnel restoration over the conventional box or slot preparation includes being more conservative and increasing tooth integrity and strength by preserving the marginal ridge.
Cheung, C, Chu, CH, Mei, L, Nalliah, RP
openaire   +7 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Extraction of Sparse Vegetation Cover in Deserts Based on UAV Remote Sensing

open access: yesRemote Sensing
The unique characteristics of desert vegetation, such as different leaf morphology, discrete canopy structures, sparse and uneven distribution, etc., pose significant challenges for remote sensing-based estimation of fractional vegetation cover (FVC ...
Jie Han   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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