Results 71 to 80 of about 3,367,709 (291)
Maximum Likelihood with Auxiliary Information
Analysis of survey data does not happen in a vacuum. We typically know more about the target population than just the data observed in the survey. In some cases this extra information can be incorporated via calibration of survey weights.
Wang, Suojin, Chambers, Ray
core +1 more source
The study was conducted from January to November, 2022 at G.B. Pant University of Agriculture and Technology, Pantnagar, with the objective of ranking sires based on first lactation traits.
Shashikant +3 more
doaj +1 more source
Restricted Maximum Likelihood Estimation in Generalized Linear Mixed Models
Restricted maximum likelihood (REML) estimation is a widely accepted and frequently used method for fitting linear mixed models, with its principal advantage being that it produces less biased estimates of the variance components. However, the concept of REML does not immediately generalize to the setting of nonnormally distributed responses, and it is
Luca Maestrini +2 more
openaire +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
On non-negative estimation of variance components in mixed linear models
Alternative estimators have been derived for estimating the variance components according to Iterative Almost Unbiased Estimation (IAUE). As a result two modified IAUEs are introduced.
Heba A. El Leithy +2 more
doaj +1 more source
Genetic analysis of growth curve in Moghani Sheep using Bayesian and restricted maximum likelihood. [PDF]
Rashedi Dehsahraei A +7 more
europepmc +1 more source
Consistency of restricted maximum likelihood estimators of principal components
In this paper we consider two closely related problems : estimation of eigenvalues and eigenfunctions of the covariance kernel of functional data based on (possibly) irregular measurements, and the problem of estimating the eigenvalues and eigenvectors of the covariance matrix for high-dimensional Gaussian vectors. In Peng and Paul (2007), a restricted
Paul, Debashis, Peng, Jie
openaire +3 more sources
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Genetic analysis of growth traits in Iranian Makuie sheep breed
The Makuie sheep is a fat-tailed sheep breed which can be found in the Azerbaijan province of Iran. In 1986, a Makuie sheep breeding station was established in the city of Maku in order to breed, protect and purify this breed.
Mohammad Farhadian +5 more
doaj +1 more source

