Results 91 to 100 of about 178,886 (297)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Lack-of-fit tests in semiparametric mixed models. [PDF]

open access: yes
In this paper we obtain the asymptotic distribution of restricted likelihood ratio tests in mixed linear models with a fixed and finite number of random effects.
Claeskens, Gerda   +2 more
core  

Pooled incidence of snakebite, REML-Restricted Maximum Likelihood.

open access: yes
Pooled incidence of snakebite, REML-Restricted Maximum Likelihood.
Afsana Afroz (6093077)   +4 more
core   +1 more source

MIXED-EFFECT MODELS WITH RESTRICTED MAXIMUM LIKELIHOOD (REML), BOOT-STRAPPED REML AND BAYESIAN INFERENCE IN APPLICATION OF GAPMINDER DATA

open access: yesBarekeng
Mixed effects model combines fixed effects and random effects, allowing for the analysis of data with both fixed and random variations. This modeling approach is widely utilized across various fields.
Asysta Amalia Pasaribu   +2 more
doaj   +1 more source

The Genetic Parameters for Milk, Fat and Protein Yields in Holstein Cows

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The aim of this study was to analyse methodology of genetic parameters estimation and breeding value prediction for milk, fat and protein yield in the first lactation of Holstein cattle using Best Linear Unbiased Prediction procedure- Restricted Maximum ...
Rodica Stefania Pelmus   +5 more
doaj  

Alternative implementations of Monte Carlo EM algorithms for likelihood inferences

open access: yesGenetics Selection Evolution, 2001
Two methods of computing Monte Carlo estimators of variance components using restricted maximum likelihood via the expectation-maximisation algorithm are reviewed.
Sorensen Daniel, García-Cortés Louis
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Restricted maximum likelihood (REML) multiple meta-regression for field of view and tracker's DoF.

open access: yes, 2014
Restricted maximum likelihood (REML) multiple meta-regression for field of view and tracker's DoF.
Harold T. Nefs (480894)   +4 more
core   +1 more source

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