Results 21 to 30 of about 1,391,894 (226)

Restriction-modification systems in Mycoplasma spp

Genetics and Molecular Biology, 2007
Restriction and Modification (R-M) systems are present in all Mycoplasma species sequenced so far. The presence of these genes poses barriers to gene transfer and could protect the cell against phage infections.
Marcelo Brocchi, Ana Tereza Ribeiro de Vasconcelos, Arnaldo Zaha   +2 more
doaj   +1 more source

Genetic manipulation of Staphylococci – Breaking through the barrier.

Frontiers in Cellular and Infection Microbiology, 2012
Most strains of Staphylococcus aureus and Staphylococcus epidermidis possess a strong restriction barrier that hinders exchange of DNA. Recently, major advances have been made in identifying and characterizing the restriction-modification systems ...
Ian R Monk, Timothy J Foster
doaj   +1 more source

Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids

BMC Microbiology, 2008
Background Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic analysis.
Ward Jordan D, Price Nancy L, Hobson Neil, Raivio Tracy L   +3 more
doaj   +1 more source

Type II restriction modification system in Ureaplasma parvum OMC-P162 strain. [PDF]

PLoS ONE, 2018
Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from ...
Heng Ning Wu, Yukiko Nakura, Michinobu Yoshimura, Ourlad Alzeus Gaddi Tantengco, Makoto Nomiyama, Toshimitsu Takayanagi, Tomio Fujita, Kiyoshi Yasukawa, Itaru Yanagihara   +8 more
doaj   +1 more source

Domain movement within a gene: a novel evolutionary mechanism for protein diversification. [PDF]

PLoS ONE, 2011
A protein function is carried out by a specific domain localized at a specific position. In the present study, we report that, within a gene, a specific amino acid sequence can move between a certain position and another position.
Yoshikazu Furuta, Mikihiko Kawai, Ikuo Uchiyama, Ichizo Kobayashi   +3 more
doaj   +1 more source

Restriction Modification Systems as Engines of Diversity

Frontiers in Microbiology, 2015
Restriction modification (RM) systems provide protection against a broad spectrum of phages. However, the likelihood of a phage permanently bypassing this can be as high as 0.1 per infection (Korona et al., J. Gen. Microbiol.
Kim eSneppen, Szabolcs eSemsey, Aswin Sai Narain Seshasayee, Sandeep eKrishna   +3 more
doaj   +1 more source

Fourier restriction to polynomial curves I: a geometric inequality [PDF]

, 2010
We prove a Fourier restriction result for general polynomial curves in Rd. Measuring the Fourier restriction with respect to the affine arclength measure of the curve, we obtain a universal estimate for the class of all polynomial curves of bounded ...
Wright, James, Wright, J., null Spyridon Dendrinos, null James Wright, Dendrinos, Spyridon, Dendrinos, S.   +5 more
core   +1 more source

Functional comparison of anti-restriction and anti-methylation activities of ArdA, KlcA, and KlcAHS from Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2022
Anti-restriction proteins are typically encoded by plasmids, conjugative transposons, or phages to improve their chances of entering a new bacterial host with a type I DNA restriction and modification (RM) system.
Huimin Chen, Shuan Tao, Na Li, Fang Wang, Lei Wang, Yu Tang, Wei Liang   +6 more
doaj   +1 more source

Epigenetic Regulation of Virulence and Immunoevasion by Phase-Variable Restriction-Modification Systems in Bacterial Pathogens

, 2020
Human-adapted bacterial pathogens use a mechanism called phase variation to randomly switch the expression of individual genes to generate a phenotypically diverse population to adapt to challenges within and between human hosts.
Atack, JM, Srikhanta, YN, Jennings, MP, Seib, KL   +3 more
core   +1 more source

Restriction-modification systems of M. gallisepticum S6.

, 2022
Arrows represent the ORFs; grey, blue, green, and orange colors indicate genes hsdC (controller protein), hsdM (methyltransferase), hsdS (specificity subunit), and hsdR (restriction subunit), respectively. Ori–origin of replication.
Vadim M. Govorun (213423), Alexander A. Arzamasov (14160029), Daria V. Evsyutina (9096071), Valentina G. Ladygina (9096068), Gleb Y. Fisunov (213389), Daria S. Matyushkina (8783387), Irina A. Garanina (14160032), Tatiana A. Semashko (9645302), Olga V. Pobeguts (8497305)   +8 more
core   +1 more source