Results 21 to 30 of about 228,478 (241)

Plasmid pEC156, a Naturally Occurring Escherichia coli Genetic Element That Carries Genes of the EcoVIII Restriction-Modification System, Is Mobilizable among Enterobacteria. [PDF]

open access: yesPLoS ONE, 2016
Type II restriction-modification systems are ubiquitous in prokaryotes. Some of them are present in naturally occurring plasmids, which may facilitate the spread of these systems in bacterial populations by horizontal gene transfer.
Olesia Werbowy, Tadeusz Kaczorowski
doaj   +1 more source

Fused eco29kIR- and M genes coding for a fully functional hybrid polypeptide as a model of molecular evolution of restriction-modification systems

open access: yesBMC Evolutionary Biology, 2011
Background The discovery of restriction endonucleases and modification DNA methyltransferases, key instruments of genetic engineering, opened a new era of molecular biology through development of the recombinant DNA technology.
Solonin Alexander S   +2 more
doaj   +1 more source

Restriction-modification systems in Mycoplasma spp

open access: yesGenetics and Molecular Biology, 2007
Restriction and Modification (R-M) systems are present in all Mycoplasma species sequenced so far. The presence of these genes poses barriers to gene transfer and could protect the cell against phage infections.
Marcelo Brocchi   +2 more
doaj   +1 more source

Genetic manipulation of Staphylococci – Breaking through the barrier.

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Most strains of Staphylococcus aureus and Staphylococcus epidermidis possess a strong restriction barrier that hinders exchange of DNA. Recently, major advances have been made in identifying and characterizing the restriction-modification systems ...
Ian R Monk, Timothy J Foster
doaj   +1 more source

Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids

open access: yesBMC Microbiology, 2008
Background Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic analysis.
Ward Jordan D   +3 more
doaj   +1 more source

Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci

open access: yesNova Biotechnologica et Chimica, 2014
The complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words ...
Pristas Peter   +2 more
doaj   +1 more source

Type II restriction modification system in Ureaplasma parvum OMC-P162 strain. [PDF]

open access: yesPLoS ONE, 2018
Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from ...
Heng Ning Wu   +8 more
doaj   +1 more source

Functional comparison of anti-restriction and anti-methylation activities of ArdA, KlcA, and KlcAHS from Klebsiella pneumoniae

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Anti-restriction proteins are typically encoded by plasmids, conjugative transposons, or phages to improve their chances of entering a new bacterial host with a type I DNA restriction and modification (RM) system.
Huimin Chen   +6 more
doaj   +1 more source

Domain movement within a gene: a novel evolutionary mechanism for protein diversification. [PDF]

open access: yesPLoS ONE, 2011
A protein function is carried out by a specific domain localized at a specific position. In the present study, we report that, within a gene, a specific amino acid sequence can move between a certain position and another position.
Yoshikazu Furuta   +3 more
doaj   +1 more source

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