IS-linked movement of a restriction-modification system. [PDF]
PLoS ONE, 2011 Potential mobility of restriction-modification systems has been suggested by evolutionary/bioinformatic analysis of prokaryotic genomes. Here we demonstrate in vivo movement of a restriction-modification system within a genome under a laboratory ...
Noriko Takahashi +4 more
doaj +5 more sources
The Restriction–Modification Systems of Clostridium carboxidivorans P7 [PDF]
Microorganisms, 2023 Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming ...
Patrick Kottenhahn +4 more
doaj +5 more sources
Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018 [PDF]
Pathogens, 2020 Intensive horizontal gene transfer may generate diversity and heterogeneity within the genus Gardnerella. Restriction-modification (R-M) systems and CRISPR-Cas are the principal defense tools against foreign DNA in bacteria.
Aistė Bulavaitė +3 more
doaj +2 more sources
A functional bacteria-derived restriction modification system in the mitochondrion of a heterotrophic protist. [PDF]
PLoS Biology, 2021 The overarching trend in mitochondrial genome evolution is functional streamlining coupled with gene loss. Therefore, gene acquisition by mitochondria is considered to be exceedingly rare.
David S Milner +4 more
doaj +2 more sources
Type II restriction modification system in Ureaplasma parvum OMC-P162 strain. [PDF]
PLoS ONE, 2018 Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from ...
Heng Ning Wu +8 more
doaj +2 more sources
From sequence to activity: the HgaI-homologous restriction modification system RM.MhoVI of Mycoplasma hominis [PDF]
BMC MicrobiologyRestriction-modification (RM) systems are widespread defense mechanisms in prokaryotes that protect the host from potentially harmful foreign DNA. They typically consist of a DNA methyltransferase (MTase), which methylates the host genome at an adenine ...
Lars Vogelgsang +5 more
doaj +2 more sources
BlihIA-A Novel Type I Restriction-Modification System from <i>Bacillus licheniformis</i> Is Sensitive to In Vitro Inhibition by ArdB Antirestriction Protein. [PDF]
Int J Mol SciKudryavtseva A +7 more
europepmc +3 more sources
Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg [PDF]
Journal of Biological EngineeringBackground Vibrio sp. dhg is a fast-growing, alginate-utilizing, marine bacterium being developed as a platform host for macroalgae biorefinery. To maximize its potential in the production of various value-added products, there is a need to expand ...
Yang Jun Shon +5 more
doaj +2 more sources
Effects of Population Dynamics on Establishment of a Restriction-Modification System in a Bacterial Host [PDF]
Molecules, 2019 In vivo dynamics of protein levels in bacterial cells depend on both intracellular regulation and relevant population dynamics. Such population dynamics effects, e.g., interplay between cell and plasmid division rates, are, however, often neglected in ...
Stefan Graovac +4 more
doaj +2 more sources
Restriction-modification systems in Mycoplasma spp [PDF]
Genetics and Molecular Biology, 2007 Restriction and Modification (R-M) systems are present in all Mycoplasma species sequenced so far. The presence of these genes poses barriers to gene transfer and could protect the cell against phage infections. The number and types of R-M genes between different Mycoplasma species are variable, which is characteristic of a polymorphism.
Marcelo Brocchi +2 more
openalex +7 more sources