Results 11 to 20 of about 605,403 (299)

Possible existence of a system similar to bacterial restriction–modification in plants

AIMS Molecular Science, 2020
The bacterial restriction–modification (R-M) system has evolved as a defense mechanism against infectious phages and other types of integration of foreign DNA fragments into the host chromosome through recombination.
Larisa I. Fedoreyeva, Boris F. Vanyushin   +1 more
doaj   +2 more sources

Restriction-modification systems in Mycoplasma spp [PDF]

Genetics and Molecular Biology, 2007
Restriction and Modification (R-M) systems are present in all Mycoplasma species sequenced so far. The presence of these genes poses barriers to gene transfer and could protect the cell against phage infections. The number and types of R-M genes between different Mycoplasma species are variable, which is characteristic of a polymorphism.
Marcelo Brocchi, Ana Tereza Ribeiro de Vasconcelos, Arnaldo Zaha   +2 more
openalex   +7 more sources

The restriction impacts of the Type III restriction-modification system on the transmission dynamics of antimicrobial resistance genes in Campylobacter jejuni [PDF]

Frontiers in Microbiology
IntroductionThe spread of antibiotic resistance genes among Campylobacter jejuni (C. jejuni) is a serious problem, and the effects of the restriction-modification (R-M) system on the transmission dynamics of these genes in C.
Yu Qiu, Pengbo Guo, Hui Tian, Ye Zhou, Hongling Wen, Hao Liang   +5 more
doaj   +2 more sources

Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018 [PDF]

Pathogens, 2020
Intensive horizontal gene transfer may generate diversity and heterogeneity within the genus Gardnerella. Restriction-modification (R-M) systems and CRISPR-Cas are the principal defense tools against foreign DNA in bacteria.
Aistė Bulavaitė, Indre Dalgediene, Vilma Michailoviene, Milda Pleckaityte   +3 more
doaj   +2 more sources

A functional bacteria-derived restriction modification system in the mitochondrion of a heterotrophic protist. [PDF]

PLoS Biology, 2021
The overarching trend in mitochondrial genome evolution is functional streamlining coupled with gene loss. Therefore, gene acquisition by mitochondria is considered to be exceedingly rare.
David S Milner, Jeremy G Wideman, Courtney W Stairs, Cory D Dunn, Thomas A Richards   +4 more
doaj   +2 more sources

Type II restriction modification system in Ureaplasma parvum OMC-P162 strain. [PDF]

PLoS ONE, 2018
Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from ...
Heng Ning Wu, Yukiko Nakura, Michinobu Yoshimura, Ourlad Alzeus Gaddi Tantengco, Makoto Nomiyama, Toshimitsu Takayanagi, Tomio Fujita, Kiyoshi Yasukawa, Itaru Yanagihara   +8 more
doaj   +2 more sources

From sequence to activity: the HgaI-homologous restriction modification system RM.MhoVI of Mycoplasma hominis [PDF]

BMC Microbiology
Restriction-modification (RM) systems are widespread defense mechanisms in prokaryotes that protect the host from potentially harmful foreign DNA. They typically consist of a DNA methyltransferase (MTase), which methylates the host genome at an adenine ...
Lars Vogelgsang, Manuel Dolgopolow-Schmidt, Azlan Nisar, Dana Bäcker, Alexander T. Dilthey, Birgit Henrich   +5 more
doaj   +2 more sources

Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities. [PDF]

Nucleic Acids Res, 2015
The restriction-modification systems use epigenetic modification to distinguish between self and nonself DNA. A modification enzyme transfers a methyl group to a base in a specific DNA sequence while its cognate restriction enzyme introduces breaks in ...
Fukuyo M, Nakano T, Zhang Y, Furuta Y, Ishikawa K, Watanabe-Matsui M, Yano H, Hamakawa T, Ide H, Kobayashi I.   +9 more
europepmc   +4 more sources

Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg [PDF]

Journal of Biological Engineering
Background Vibrio sp. dhg is a fast-growing, alginate-utilizing, marine bacterium being developed as a platform host for macroalgae biorefinery. To maximize its potential in the production of various value-added products, there is a need to expand ...
Yang Jun Shon, Dongyeop Baek, Su Bin Jin, Woo Jae Kim, Gyoo Yeol Jung, Hyun Gyu Lim   +5 more
doaj   +2 more sources

Individual- and Population-based Diversity in Restriction-modification Systems

Bulletin of Mathematical Biology, 2000
Restriction-modification (RM) systems are cognate gene complexes that code for an endonuclease and a methylase. They are often thought to have developed in bacteria as protection against invading genetic material, e.g., phage DNA. The high diversity of RM systems, as observed in nature, is often ascribed to the coevolution of RM systems (which 'invent'
Ludo Pagie
openalex   +4 more sources