Results 31 to 40 of about 186,000 (245)

Transcription regulation of restriction-modification system Esp1396I [PDF]

Nucleic Acids Research, 2009
Abstract The convergently transcribed restriction (R) and methylase (M) genes of the Restriction–Modification system Esp1396I are tightly regulated by a controller (C) protein that forms part of the CR operon. We have mapped the transcriptional start sites from each promoter and examined the regulatory role of C.Esp1396I in vivo and in ...
Bogdanova, E., Zakharova, M., Streeter, Simon, Taylor, J., Heyduk, T., Kneale, Geoff, Severinov, K.   +6 more
openaire   +3 more sources

Structural basis for broad anti-phage immunity by DISARM

Nature Communications, 2022
DISARM (Defense Island System Associated with Restriction Modification) systems can provide bacteria with protection against a wide range of phage. Here, Bravo et al.
Jack P. K. Bravo, Cristian Aparicio-Maldonado, Franklin L. Nobrega, Stan J. J. Brouns, David W. Taylor   +4 more
doaj   +1 more source

The Restriction–Modification Systems of Clostridium carboxidivorans P7

Microorganisms, 2023
Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming ...
Patrick Kottenhahn, Gabriele Philipps, Boyke Bunk, Cathrin Spröer, Stefan Jennewein   +4 more
doaj   +1 more source

Bacterial Autoimmunity Due to a Restriction-Modification System [PDF]

Current Biology, 2016
Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M) and cognate restriction endonuclease (R).
Pleška, Maroš, Qian, Long, Okura, Reiko, Bergmiller, Tobias, Wakamoto, Yuichi, Kussell, Edo, Guet, Călin C.   +6 more
openaire   +2 more sources

Transcription regulation of restriction-modification system Ecl18kI [PDF]

Nucleic Acids Research, 2009
Restriction-modification (R-M) system Ecl18kI is representative of R-M systems whose coordinated transcription is achieved through a separate DNA-binding domain of the methyltransferase. M.Ecl18kI recognizes an operator sequence located in the noncoding region that separates the divergently transcribed R and M genes.
Protsenko, Alexey, Zakharova, Marina, Nagornykh, Maxim, Solonin, Alexander, Severinov, Konstantin   +4 more
openaire   +2 more sources

Adaptive Tracking Control of an Electro-Pneumatic Clutch Actuator [PDF]

Modeling, Identification and Control, 2003
This paper deals with the application of a simple adaptive algorithm for robust tracking control of an electro-pneumatic clutch actuator with output feedback.
Glenn-Ole Kaasa, Masanori Takahashi
doaj   +1 more source

To be or not to be: regulation of restriction–modification systems and other toxin–antitoxin systems [PDF]

Nucleic Acids Research, 2013
One of the simplest classes of genes involved in programmed death is that containing the toxin-antitoxin (TA) systems of prokaryotes. These systems are composed of an intracellular toxin and an antitoxin that neutralizes its effect. These systems, now classified into five types, were initially discovered because some of them allow the stable ...
Mruk, Iwona, Kobayashi, Ichizo
openaire   +2 more sources

Organization of restriction-modification systems

Nucleic Acids Research, 1991
The genes for over 100 restriction-modification systems have now been cloned, and approximately one-half have been sequenced. Despite their similar function, they are exceedingly heterogeneous. The heterogeneity is evident at three levels: in the gene arrangements; in the enzyme compositions; and in the protein sequences. This paper summarizes the main
openaire   +3 more sources

The Neisseria gonorrhoeae S.NgoVIII restriction/modification system: a type IIs system homologous to the Haemophilus parahaemolyticus HphI restriction/modification system [PDF]

Nucleic Acids Research, 1997
Strains of Neisseria gonorrhoeae possess numerous restriction-modification (R-M) systems. One of these systems, which has been found in all strains tested, encodes the S. NgoVIII specificity (5'TCACC 3') R-M system. We cloned two adjacent methyltransferase genes (dcmH and damH), each encoding proteins whose actions protect DNA from digestion by R.HphI ...
J S, Gunn, D C, Stein
openaire   +2 more sources

Avoidance of recognition sites of restriction-modification systems is a widespread but not universal anti-restriction strategy of prokaryotic viruses

BMC Genomics, 2018
Background Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host DNA are ...
I. S. Rusinov, A. S. Ershova, A. S. Karyagina, S. A. Spirin, A. V. Alexeevski   +4 more
doaj   +1 more source