Broadness and specificity: ArdB, ArdA, and Ocr against various restriction-modification systems
Frontiers in Microbiology, 2023 ArdB, ArdA, and Ocr proteins inhibit the endonuclease activity of the type I restriction-modification enzymes (RMI). In this study, we evaluated the ability of ArdB, ArdA, and Ocr to inhibit different subtypes of Escherichia coli RMI systems (IA, IB, and
Anna A. Kudryavtseva +12 more
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Regulation of gene expression in restriction-modification system Eco29kI [PDF]
Nucleic Acids Research, 2011 The Eco29kI restriction-modification (R-M) system consists of two partially overlapping genes, eco29kIR, encoding a restriction endonuclease and eco29kIM, encoding methyltransferase.
Maxim Nagornykh +5 more
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Evolutionary genome engineering using a restriction–modification system [PDF]
Nucleic Acids Research, 2011 Modification of complex microbial cellular processes is often necessary to obtain organisms with particularly favorable characteristics, but such experiments can take many generations to achieve.
Yoko Asakura +2 more
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A bistable hysteretic switch in an activator-repressor regulated restriction-modification system. [PDF]
Nucleic Acids Res, 2013 Restriction–modification (RM) systems are extremely widespread among bacteria and archaea, and are often specified by mobile genetic elements. In type II RM systems, where the restriction endonuclease (REase) and protective DNA methyltransferase (MTase ...
Williams K, Savageau MA, Blumenthal RM.
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Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg [PDF]
Journal of Biological EngineeringBackground Vibrio sp. dhg is a fast-growing, alginate-utilizing, marine bacterium being developed as a platform host for macroalgae biorefinery. To maximize its potential in the production of various value-added products, there is a need to expand ...
Yang Jun Shon +5 more
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Effects of Population Dynamics on Establishment of a Restriction-Modification System in a Bacterial Host [PDF]
Molecules, 2019 In vivo dynamics of protein levels in bacterial cells depend on both intracellular regulation and relevant population dynamics. Such population dynamics effects, e.g., interplay between cell and plasmid division rates, are, however, often neglected in ...
Stefan Graovac +4 more
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Improved genetic transformation by disarmament of type II Restriction-Modification system in Streptococcus zooepidemicus. [PDF]
3 Biotech, 2022 Gao W, Xie Y, Zuo M, Zhang G, Liu H.
europepmc +3 more sources
Bacterial Autoimmunity Due to a Restriction-Modification System [PDF]
Current Biology, 2016 Maroš Pleška +6 more
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A Type 3 Prophage of ‘Candidatus Liberibacter asiaticus’ Carrying a Restriction-Modification System [PDF]
Phytopathology, 2017 Zheng Zheng +5 more
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The EcoKI type I restriction-modification system in Escherichia coli affects but is not an absolute barrier for conjugation. [PDF]
J Bacteriol, 2015 Roer L, Aarestrup FM, Hasman H.
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