Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168 [PDF]
, 2016 Phase-variable restriction-modification systems are a feature of a diverse range of bacterial species. Stochastic, reversible switches in expression of the methyltransferase produces variation in methylation of specific sequences.
Awais Anjum +13 more
core +2 more sources
Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementation [PDF]
, 2012 Ethanolamine phosphoglycerol (EPG) is a protein modification attached exclusively to eukaryotic elongation factor 1A (eEF1A). In mammals and plants, EPG is linked to conserved glutamate residues located in eEF1A domains II and III, whereas in the ...
Eva Greganova +5 more
core +8 more sources
Methylome-dependent transformation of emm1 group A streptococci
mBio, 2023 Genetic intractability presents a fundamental barrier to the manipulation of bacteria, hindering advancements in microbiological research. Group A Streptococcus (GAS), a lethal human pathogen currently associated with an unprecedented surge of infections
Joana Alves +4 more
doaj +1 more source
bioRxiv, 2023 Many novel traits such as antibiotic resistance are spread by plasmids between species. Yet plasmids have different host ranges. Restriction-modification systems (R-M systems) are by far the most abundant bacterial defense system and therefore represent ...
L. Shaw, E. Rocha, R. MacLean
semanticscholar +1 more source
Influence of gestational salt restriction in fetal growth and in development of diseases in adulthood [PDF]
, 2016 Review. Recent studies reported the critical role of the intrauterine environment of a fetus in growth or the development of disease in adulthood. In this article we discussed the implications of salt restriction in growth of a fetus and the development ...
Katoh, M +5 more
core +1 more source
Convergence of DNA methylation and phosphorothioation epigenetics in bacterial genomes [PDF]
, 2017 Explosive growth in the study of microbial epigenetics has revealed a diversity of chemical structures and biological functions of DNA modifications in restriction-modification (R-M) and basic genetic processes.
Chen, Chao +10 more
core +1 more source
Structural basis for broad anti-phage immunity by DISARM
Nature Communications, 2022 DISARM (Defense Island System Associated with Restriction Modification) systems can provide bacteria with protection against a wide range of phage. Here, Bravo et al.
Jack P. K. Bravo +4 more
doaj +1 more source
The Restriction–Modification Systems of Clostridium carboxidivorans P7
Microorganisms, 2023 Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming ...
Patrick Kottenhahn +4 more
doaj +1 more source
Possible existence of a system similar to bacterial restriction–modification in plants
AIMS Molecular Science, 2020 The bacterial restriction–modification (R-M) system has evolved as a defense mechanism against infectious phages and other types of integration of foreign DNA fragments into the host chromosome through recombination.
Larisa I. Fedoreyeva +1 more
doaj +1 more source
Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and more [PDF]
, 2009 The Dam methylase of gamma-proteobacteria and the CcrM methylase of alpha-proteobacteria catalyze an identical reaction (methylation of adenosine moieties using S-adenosyl-methionine as methyl donor) at similar DNA targets (GATC and GANTC, respectively).
Casadesús Pursals, Josep +1 more
core +2 more sources