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Chemopreventive effects of resveratrol and resveratrol derivatives
Annals of the New York Academy of Sciences, 2011Resveratrol is considered to have a number of beneficial effects. Recently, our group modified the molecule and synthesized a number of compounds with different biochemical effects. Polymethoxy and polyhydroxy derivatives of resveratrol were shown to inhibit tumor cell growth in various cell lines and inflammation pathways (cyclooxygenases activity ...
Szekeres, Thomas +4 more
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2017
Cardiovascular disease (CVD) is the leading cause of death in both men and women and has largely been attributed to genetic makeup and lifestyle factors. However, genetic regulation does not fully explain the pathophysiology. Recently, epigenetic regulation, the regulation of the genetic code by modifications that affect the transcription and ...
Catherine A. Powell +3 more
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Cardiovascular disease (CVD) is the leading cause of death in both men and women and has largely been attributed to genetic makeup and lifestyle factors. However, genetic regulation does not fully explain the pathophysiology. Recently, epigenetic regulation, the regulation of the genetic code by modifications that affect the transcription and ...
Catherine A. Powell +3 more
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Resveratrol and chemoprevention
Cancer Letters, 2009Resveratrol is a phytoalexin, highly abundant in skins of red grapes and moderately abundant in peanuts and blueberries. Originally a constituent of oriental medicines, it has lately been rediscovered for a plethora of beneficial properties such as anti-cancer, anti-aging, antiviral, cardiovascular and neuroprotective effects, thereby making it one of ...
Shyamal K, Goswami, Dipak K, Das
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Critical Reviews in Food Science and Nutrition, 2013
Peanuts are important dietary food source of resveratrol with potent antioxidant properties implicated in reducing risk of cancer, cardiovascular and Alzheimer's disease, and delaying aging. Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound produced in response to a variety of biotic and abiotic stresses.
Jocelyn M, Sales, Anna V A, Resurreccion
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Peanuts are important dietary food source of resveratrol with potent antioxidant properties implicated in reducing risk of cancer, cardiovascular and Alzheimer's disease, and delaying aging. Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound produced in response to a variety of biotic and abiotic stresses.
Jocelyn M, Sales, Anna V A, Resurreccion
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Bioavailability of resveratrol
Annals of the New York Academy of Sciences, 2011This paper reviews our current understanding of the absorption, bioavailability, and metabolism of resveratrol, with an emphasis on humans. The oral absorption of resveratrol in humans is about 75% and is thought to occur mainly by transepithelial diffusion. Extensive metabolism in the intestine and liver results in an oral bioavailability considerably
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Resveratrol: A Polyphenol for All Seasons
2005The history of resveratrol, the active ingredient in red grapes, peanuts, berries, and several other food plants, indirectly dates back to the Ayurveda, the ancient Indian treatise on the science of longevity. Although once considered a disadvantage, resveratrol’s ability to modulate multiple cellular targets makes it suitable for the prevention and ...
Bharat Aggarwal, Shishir Shishodia
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Science Translational Medicine, 2011
A small study demonstrates the salutary metabolic effects of an ingredient from the fruit of the vine.
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A small study demonstrates the salutary metabolic effects of an ingredient from the fruit of the vine.
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