Results 211 to 220 of about 60,412 (260)
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Current Opinion in Genetics & Development, 1996
RET mutations have been identified as the underlying cause of two congenital diseases that predominately affect tissues of neural crest origin: the MEN 2 cancer syndromes and a proportion of cases of dominantly inherited Hirschsprung disease, a disorder of gut development.
Y F, Mak, B A, Ponder
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RET mutations have been identified as the underlying cause of two congenital diseases that predominately affect tissues of neural crest origin: the MEN 2 cancer syndromes and a proportion of cases of dominantly inherited Hirschsprung disease, a disorder of gut development.
Y F, Mak, B A, Ponder
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2009
The RET protooncogene encodes a transmembrane receptor tyrosine kinase (RTK) with affinity for multiple ligands, including glial cell line-derived neurotrophic factor (GDNF). It was first described in 1985 by Takahashi and others, who identified rearrangements in the gene from human lymphoma DNA with transforming activity in a transfected cell line [1].
Amber L, Traugott, Jeffrey F, Moley
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The RET protooncogene encodes a transmembrane receptor tyrosine kinase (RTK) with affinity for multiple ligands, including glial cell line-derived neurotrophic factor (GDNF). It was first described in 1985 by Takahashi and others, who identified rearrangements in the gene from human lymphoma DNA with transforming activity in a transfected cell line [1].
Amber L, Traugott, Jeffrey F, Moley
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2006
The human RET (REarranged during transfection) gene maps on chromosome 10q11.2 and codes for a single pass transmembrane protein.The intracellular portion features a typical tyrosine kinase domain.RET is expressed primarily in peripheral enteric, sympathetic and sensory neurons, and in central motor, dopaminergic and noradrenergic neurons.
VECCHIO, GIANCARLO +2 more
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The human RET (REarranged during transfection) gene maps on chromosome 10q11.2 and codes for a single pass transmembrane protein.The intracellular portion features a typical tyrosine kinase domain.RET is expressed primarily in peripheral enteric, sympathetic and sensory neurons, and in central motor, dopaminergic and noradrenergic neurons.
VECCHIO, GIANCARLO +2 more
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Thyroid : official journal of the American Thyroid Association, 2005
Somatic rearrangement of the tyrosine kinase receptor RET is restricted to papillary thyroid carcinoma (PTC). The prevalence of RET/PTC1, RET/PTC2, and RET/PTC3 has been found to vary between 0% and 20% in most series of sporadic (nonradiation-induced) PTCs analyzed by type-specific reverse transcription-polymerase chain reaction (RT-PCR) alone ...
Rue-Tsuan, Liu +8 more
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Somatic rearrangement of the tyrosine kinase receptor RET is restricted to papillary thyroid carcinoma (PTC). The prevalence of RET/PTC1, RET/PTC2, and RET/PTC3 has been found to vary between 0% and 20% in most series of sporadic (nonradiation-induced) PTCs analyzed by type-specific reverse transcription-polymerase chain reaction (RT-PCR) alone ...
Rue-Tsuan, Liu +8 more
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Cancer Letters, 2004
Glial cell line-derived neurotrophic factor (GDNF), a ligand of RET tyrosine kinase, and its family ligands promote the survival and differentiation of a variety of neurons. Gene ablation studies have revealed that the GDNF-RET receptor system is essential for the development of kidney and peripheral neurons, including sympathetic, parasympathetic and ...
Masatoshi, Ichihara +2 more
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Glial cell line-derived neurotrophic factor (GDNF), a ligand of RET tyrosine kinase, and its family ligands promote the survival and differentiation of a variety of neurons. Gene ablation studies have revealed that the GDNF-RET receptor system is essential for the development of kidney and peripheral neurons, including sympathetic, parasympathetic and ...
Masatoshi, Ichihara +2 more
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Pituitary, 2006
The RET proto-oncogene encodes a receptor tyrosine kinase that is a main component of the signaling pathway activated by the glial cell line-derived neurotrophic factor family ligands. Gene targeting studies revealed that signaling through RET plays a crucial role in neuronal and renal organogenesis. It is well-known that germline mutations in RET lead
Yoshiki, Murakumo +4 more
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The RET proto-oncogene encodes a receptor tyrosine kinase that is a main component of the signaling pathway activated by the glial cell line-derived neurotrophic factor family ligands. Gene targeting studies revealed that signaling through RET plays a crucial role in neuronal and renal organogenesis. It is well-known that germline mutations in RET lead
Yoshiki, Murakumo +4 more
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2009
The expression of RET gene that encodes a transmembrane receptor with tyrosine kinase activi- ty, was studied on 59 post-Chernobyl thyroid tumors (35 papillary carcinomas and 24 follicular adenomas). It is shown that the majority of tumors, both benign and malignant, exhibits RET expression. The presence of gene RET in thyroid tumors was not associated
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The expression of RET gene that encodes a transmembrane receptor with tyrosine kinase activi- ty, was studied on 59 post-Chernobyl thyroid tumors (35 papillary carcinomas and 24 follicular adenomas). It is shown that the majority of tumors, both benign and malignant, exhibits RET expression. The presence of gene RET in thyroid tumors was not associated
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2015
The RET (REarranged during Transfection) gene encodes the tyrosine kinase membrane receptor (RET) for glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL). The human RET gene is located on the long arm of chromosome 10 (10q11.2). RET protein contains an N-terminal glycosylated extracellular portion, with four cadherin-like and one ...
Melillo Rosa Marina, Santoro Massimo
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The RET (REarranged during Transfection) gene encodes the tyrosine kinase membrane receptor (RET) for glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL). The human RET gene is located on the long arm of chromosome 10 (10q11.2). RET protein contains an N-terminal glycosylated extracellular portion, with four cadherin-like and one ...
Melillo Rosa Marina, Santoro Massimo
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