Results 31 to 40 of about 10,171 (216)

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

ONTOLOGICAL AND CONTEXTUAL POSITION OF TIME: BETWEEN AEON AND RETARDATIONS OF NOTHING

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії, 2020
Research on the negative foundations of time will not lose its relevance as long as the connection, stated by M. Heidegger in 1927, remains legitimate and systemically justified.
Darya A. Zakhlypa
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Clinico-Epidemiological Study of Iraqi Children with Sanjad Sakati Syndrome

Medical Journal of Babylon
Background: Sanjad Sakati syndrome (SSS), also known as hypoparathyroidism–retardation–dysmorphism, is a very rare genetic disease caused by a mutation in the tubulin co-factor E gene.
Munib Ahmed Al-Zubaidi, Muneera Fadhil Ridha, Hana Ali Abd-Aljabar   +2 more
doaj   +1 more source

Multiple Coupled Mathematical Model for Radionuclide Electromigration Experiments in Granites

He huaxue yu fangshe huaxue
Granite is considered an ideal medium for geological disposal of nuclear waste due to its unique stability and wide distribution. When the repository media barrier fails, granite serves as the peripheral rock medium.
Xiao-jie LI, Kai-xuan TAN, Long-cheng LIU, Yong-mei LI, Chun-guang LI, Zhi ZOU, Qi LIU   +6 more
doaj   +1 more source

Human urinary sulfatides in patients with sulfatidosis (metachromatic leukodystrophy)

Journal of Lipid Research, 1971
The excretion of sulfatides in human urine was studied. 24-hr urine collections were filtered. Urinary glycolipids were extracted from the filter paper and fractionated on diethylaminoethyl cellulose and silicic acid columns, and by thin-layer ...
MICHEL PHILIPPART, LOUIS SARLIEVE, COLETTE MEURANT, LASZLO MECHLER   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Determination of less than a nanomol of cerebrosides by high performance liquid chromatography with gradient elution analysis

Journal of Lipid Research, 1977
A gradient elution high performance liquid chromatography method with detection at 230 nm for the analysis of perbenzoylated cerebrosides containing hydroxy and nonhydroxy fatty acids is described.
F B Jungalwala, L Hayes, R H McCluer
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source