Results 91 to 100 of about 47,239 (175)

Interactions between Apolipoprotein E Metabolism and Retinal Inflammation in Age-Related Macular Degeneration

Life, 2021
Age-related macular degeneration (AMD) is a multifactorial retinal disorder that is a major global cause of severe visual impairment. The development of an effective therapy to treat geographic atrophy, the predominant form of AMD, remains elusive due to
Monica L. Hu, Joel Quinn, Kanmin Xue
doaj   +1 more source

Image Registration and Multimodal Imaging of Reticular Pseudodrusen

Investigative Opthalmology & Visual Science, 2011
To characterize reticular pseudodrusen (RPD) by using a point-to-point comparison of the reticular pattern on infrared reflectance (IR), autofluorescence (AF), and red-free (RF) images registered with en face sections of the choroid from spectral domain optical coherence tomography (SD-OCT) scans.A cross-sectional, retrospective study of all patients ...
Mahsa A, Sohrab, R Theodore, Smith, Hani, Salehi-Had, SriniVas R, Sadda, Amani A, Fawzi   +4 more
openaire   +2 more sources

High risk does not guarantee high accuracy—Evaluating the prognostic accuracy of OCT biomarkers for predicting late AMD

Ophthalmic and Physiological Optics, Volume 45, Issue 6, Page 1293-1301, September 2025.
Abstract Purpose The translation of high‐risk biomarkers into accurate predictions of late age‐related macular degeneration (AMD) may be limited by biomarker prevalence, subjective identification and competing risks from concurrent biomarkers. This study evaluates the prognostic performance of key optical coherence tomography (OCT) biomarkers for ...
Matt Trinh, Rene Cheung, Judy Nam, David Ng, Lisa Nivison‐Smith, Angelica Ly   +5 more
wiley   +1 more source

PATHOLOGIC INSIGHTS FROM INTEGRATED IMAGING OF RETICULAR PSEUDODRUSEN IN AGE-RELATED MACULAR DEGENERATION

, 2011
Purpose: The purpose of this study was to analyze the integrated infrared reflectance, fundus autofluorescence, and fluorescein angiography (integrated confocal scanning laser ophthalmoscopy fundus imaging) features of reticular pseudodrusen and eye ...
Massamba N, Souied EH, Coscas G, Martinelli D, QUERQUES , GIUSEPPE, Querques L, Soubrane G   +6 more
core   +1 more source

Evaluation of coronary artery disease as a risk factor for reticular pseudodrusen [PDF]

British Journal of Ophthalmology, 2017
PurposeReticular pseudodrusen (RPD) are a risk factor for late age-related macular degeneration (AMD). Associations between RPD and coronary artery disease (CAD) have been reported from small case–control studies. This study investigated the association of RPD within a predominantly CAD cohort.MethodsA subgroup of subjects from a multicentre randomised
McCarter, Rachel V, McKay, Gareth J, Quinn, Nicola B, Chakravarthy, Usha, MacGillivray, Tom J, Robertson, Gavin, Pellegrini, Enrico, Trucco, Emanuele, Williams, Michelle C, Peto, Tunde, Dhillon, Baljean, van Beek, Edwin Jr, Newby, David E, Kee, Frank, Young, Ian S, Hogg, Ruth E   +15 more
openaire   +5 more sources

Nocturnal hypoxia and age‐related macular degeneration

Clinical &Experimental Ophthalmology, Volume 52, Issue 9, Page 973-980, December 2024.
Abstract Background Nocturnal hypoxia is common, under‐diagnosed and is found in the same demographic at risk of age‐related macular degeneration (AMD). The objective of this study was to determine any association between nocturnal hypoxia and AMD, its severity, and the high‐risk sub‐phenotype of reticular pseudodrusen (RPD).
Attiqa Chaudhary, Carla J. Abbott, Zhichao Wu, Wendy Y. Fang, Palaniraj R. Raj, Matthew Naughton, Wilson J. Heriot, Robyn H. Guymer   +7 more
wiley   +1 more source

Appearance of medium-large drusen and reticular pseudodrusen on adaptive optics in age-related macular degeneration

, 2014
Purpose To investigate the appearance of medium-large drusen and reticular pseudodrusen on adaptive optics (AO). Methods In 14 consecutive patients, AO infrared (IR) images were overlaid with confocal scanning-laser-ophthalmoscope IR reflectance images ...
Blanco Garavito R, Souied EH, Capuano V, Poulon F, Pedinielli A, QUERQUES , GIUSEPPE, Kamami Levy C, Georges A   +7 more
core   +1 more source

Relative ellipsoid zone reflectivity and its association with disease severity in age-related macular degeneration: a MACUSTAR study report

Scientific Reports, 2022
Quantification of the relative ellipsoid zone reflectivity (rEZR) might be a structural surrogate parameter for an early disease progression in the context of age-related macular degeneration (AMD).
Marlene Saßmannshausen, Charlotte Behning, Ben Isselmann, Matthias Schmid, Robert P. Finger, Frank G. Holz, Steffen Schmitz-Valckenberg, Maximilian Pfau, MACUSTAR Consortium, Sarah Thiele   +9 more
doaj   +1 more source

Autophagy in drusen biogenesis secondary to age‐related macular degeneration

Acta Ophthalmologica, Volume 102, Issue 7, Page 759-772, November 2024.
Abstract Age‐related macular degeneration (AMD) is an emerging cause of blindness in aged people worldwide. One of the key signs of AMD is the degeneration of the retinal pigment epithelium (RPE), which is indispensable for the maintenance of the adjacent photoreceptors.
Juha M. T. Hyttinen, Ali Koskela, Janusz Blasiak, Kai Kaarniranta   +3 more
wiley   +1 more source

A pilot quantitative study of topographic correlation between reticular pseudodrusen and the choroidal vasculature using en face optical coherence tomography. [PDF]

PLoS ONE, 2014
To analyze the topographic correlation between reticular pseudodrusen (RPD) visualized on infrared reflectance (IR) and choroidal vasculature using en-face volumetric spectral-domain optical coherence tomography (SD-OCT).A masked observer marked ...
Dilraj S Grewal, Jonathan Chou, Stuart D Rollins, Amani A Fawzi   +3 more
doaj   +1 more source