Results 31 to 40 of about 1,137 (129)

Deficits in Monocyte Function in Age Related Macular Degeneration: A Novel Systemic Change Associated With the Disease

Frontiers in Medicine, 2021
Age-related macular degeneration (AMD) is characterized by the accumulation of debris in the posterior eye. In this study we evaluated peripheral blood monocyte phagocytic function at various stages of AMD and in aged matched control participants.
Ben J. Gu, Ben J. Gu, Xin Huang, Pavan K. Avula, Emily Caruso, Candace Drysdale, Kirstan A. Vessey, Amber Ou, Christopher Fowler, Tian-Hua Liu, Yong Lin, Adam Horton, Colin L. Masters, James S. Wiley, Robyn H. Guymer, Erica L. Fletcher   +15 more
doaj   +1 more source

Choriocapillaris Nonperfusion is Associated With Poor Visual Acuity in Eyes With Reticular Pseudodrusen. [PDF]

Am J Ophthalmol, 2017
Nesper PL, Soetikno BT, Fawzi AA.
europepmc   +2 more sources

Multimodal imaging and deep learning in geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, Volume 101, Issue 8, Page 881-890, December 2023., 2023
Abstract Geographic atrophy (GA) secondary to age‐related macular degeneration is among the most common causes of irreversible vision loss in industrialized countries. Recently, two therapies have been approved by the US FDA. However, given the nature of their treatment effect, which primarily involves a relative decrease in disease progression ...
Maximilian Pfau, Sandrine H. Künzel, Kristina Pfau, Steffen Schmitz‐Valckenberg, Monika Fleckenstein, Frank G. Holz   +5 more
wiley   +1 more source

Unveiling the drivers of geographic atrophy progression in eyes with reticular pseudodrusen [PDF]

PLoS ONE
Mingui Kong, So Young Han, Sungsoon Hwang, Ga-In Lee, Je Moon Yoon, Don-Il Ham   +5 more
doaj   +1 more source

Treatment of dry age‐related macular degeneration: A review

Clinical &Experimental Ophthalmology, Volume 51, Issue 8, Page 835-852, November 2023., 2023
Abstract Age‐related macular degeneration is a global disease with a significant societal impact. The advent of anti‐vascular endothelial growth factor therapy (anti‐VEGF) has revolutionised the treatment of neovascular age‐related macular degeneration (nAMD).
Shenouda Girgis, Lawrence R. Lee
wiley   +1 more source

Optometrists' attitudes toward using OCT angiography lag behind other retinal imaging types

Ophthalmic and Physiological Optics, Volume 43, Issue 4, Page 905-915, July 2023., 2023
Abstract Purpose While optometrists' attitudes toward established retinal imaging types are generally positive, they are unknown for optical coherence tomography angiography (OCTA). We performed a cross‐sectional survey to estimate attitudes toward OCTA and identify clinician and/or practice characteristics that influence them.
Rene Cheung, Sharon Ho, Angelica Ly
wiley   +1 more source

Microperimetry to predict disease progression in eyes at high risk of age‐related macular degeneration disease: The PREVISION study

Acta Ophthalmologica, Volume 101, Issue 2, Page e135-e142, March 2023., 2023
Abstract Purpose The aim of the present study was to determine whether microperimetric parameters could predict the progression of an eye at high risk of age‐related macular degeneration (AMD) at 24 months. Methods We conducted a multicentric prospective non‐comparative open‐label study including patients with one eye in stage 4 of the Age‐Related Eye ...
Laurent Kodjikian, Catherine Creuzot‐Garcher, Jean‐François Korobelnik, Ramin Tadayoni, Ivan Delafoy, Cécilia Leal, Lorraine Bernard, Evelyne Decullier, Laure Huot, Thibaud Mathis   +9 more
wiley   +1 more source

Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina

Journal of Extracellular Vesicles, Volume 11, Issue 12, December 2022., 2022
Abstract Age‐related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis. Here we use AMD patient‐specific RPE cells with the Complement Factor H Y402H high‐risk polymorphism to perform a comprehensive analysis of ...
Marzena Kurzawa‐Akanbi, Phillip Whitfield, Florence Burté, Pietro Maria Bertelli, Varun Pathak, Mary Doherty, Birthe Hilgen, Lina Gliaudelytė, Mark Platt, Rachel Queen, Jonathan Coxhead, Andrew Porter, Maria Öberg, Daniela Fabrikova, Tracey Davey, Chia Shyan Beh, Maria Georgiou, Joseph Collin, Veronika Boczonadi, Anetta Härtlova, Michael Taggart, Jumana Al‐Aama, Viktor I Korolchuk, Christopher M Morris, Jasenka Guduric‐Fuchs, David H Steel, Reinhold J Medina, Lyle Armstrong, Majlinda Lako   +28 more
wiley   +1 more source

Spatial Analysis Reveals Vascular Changes in Retinal and Choroidal Vessel Perfusion in Intermediate AMD With Reticular Pseudodrusen. [PDF]

Invest Ophthalmol Vis Sci
Nam J, Nivison-Smith L, Trinh M.
europepmc   +3 more sources

Age‐related macular degeneration and myeloproliferative neoplasms – A common pathway

Acta Ophthalmologica, Volume 100, Issue S271, Page 3-35, October 2022., 2022
Summary Dansk Resumé (Danish summary) Aldersrelateret makuladegeneration (AMD) er den hyppigste årsag til uopretteligt synstab og blindhed i højindkomstlande. Det er en progredierende nethindesygdom som gradvist fører til ødelæggelse af de celler som er ansvarlige for vores centralsyn. De tidlige stadier er ofte asymptomatiske, imens senstadie AMD, som
Charlotte Liisborg
wiley   +1 more source