Results 51 to 60 of about 47,239 (175)

Unaffected fellow eye neovascularization in patients with type 3 neovascularization: Incidence and risk factors.

PLoS ONE, 2021
PurposeTo evaluate the incidence and risk factors of neovascularization in unaffected fellow eyes of patients diagnosed with type 3 neovascularization in Korea.MethodsThis retrospective study included 93 unaffected fellow eyes of 93 patients diagnosed ...
Jae Hyuck Kwak, Woo Kyung Park, Rae Young Kim, Mirinae Kim, Young-Gun Park, Young-Hoon Park   +5 more
doaj   +1 more source

Deficits in Monocyte Function in Age Related Macular Degeneration: A Novel Systemic Change Associated With the Disease

Frontiers in Medicine, 2021
Age-related macular degeneration (AMD) is characterized by the accumulation of debris in the posterior eye. In this study we evaluated peripheral blood monocyte phagocytic function at various stages of AMD and in aged matched control participants.
Ben J. Gu, Ben J. Gu, Xin Huang, Pavan K. Avula, Emily Caruso, Candace Drysdale, Kirstan A. Vessey, Amber Ou, Christopher Fowler, Tian-Hua Liu, Yong Lin, Adam Horton, Colin L. Masters, James S. Wiley, Robyn H. Guymer, Erica L. Fletcher   +15 more
doaj   +1 more source

The Relationship Between Reticular Pseudodrusen and Severity of AMD [PDF]

Ophthalmology, 2016
Jaclyn L, Kovach, Stephen G, Schwartz, Anita, Agarwal, Milam A, Brantley, Samuel S, Pan, Jonathan L, Haines, William K, Scott, Margaret A, Pericak-Vance   +7 more
openaire   +3 more sources

Multimodal imaging and deep learning in geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, Volume 101, Issue 8, Page 881-890, December 2023., 2023
Abstract Geographic atrophy (GA) secondary to age‐related macular degeneration is among the most common causes of irreversible vision loss in industrialized countries. Recently, two therapies have been approved by the US FDA. However, given the nature of their treatment effect, which primarily involves a relative decrease in disease progression ...
Maximilian Pfau, Sandrine H. Künzel, Kristina Pfau, Steffen Schmitz‐Valckenberg, Monika Fleckenstein, Frank G. Holz   +5 more
wiley   +1 more source

Treatment of dry age‐related macular degeneration: A review

Clinical &Experimental Ophthalmology, Volume 51, Issue 8, Page 835-852, November 2023., 2023
Abstract Age‐related macular degeneration is a global disease with a significant societal impact. The advent of anti‐vascular endothelial growth factor therapy (anti‐VEGF) has revolutionised the treatment of neovascular age‐related macular degeneration (nAMD).
Shenouda Girgis, Lawrence R. Lee
wiley   +1 more source

Optometrists' attitudes toward using OCT angiography lag behind other retinal imaging types

Ophthalmic and Physiological Optics, Volume 43, Issue 4, Page 905-915, July 2023., 2023
Abstract Purpose While optometrists' attitudes toward established retinal imaging types are generally positive, they are unknown for optical coherence tomography angiography (OCTA). We performed a cross‐sectional survey to estimate attitudes toward OCTA and identify clinician and/or practice characteristics that influence them.
Rene Cheung, Sharon Ho, Angelica Ly
wiley   +1 more source

Subretinal drusenoid deposits: An update

Taiwan Journal of Ophthalmology, 2022
A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs),
Manuel Monge, Adriana Araya, Lihteh Wu
doaj   +1 more source

Genetic Risk of Reticular Pseudodrusen in Age-Related Macular Degeneration: HTRA1/lncRNA BX842242.1 dominates, with no evidence for Complement Cascade involvement

medRxiv
GWAS Catalog Summary Statistics Data accompanying Farashi et al., preprint (https://www.medrxiv.org/content/10.1101/2024.09.26.24314339v1) and recently accepted paper in Nature Communications: HTRA1/lncRNA HTRA1-AS1 dominates in Age-Related Macular ...
S. Farashi, Carla J. Abbott, Brendan R. E. Ansell, Zhichao Wu, L. Altay, Ella Arnon, L. Arnould, Yelena Bagdasarova, Konstantinos Balaskas, Fred K Chen, Emily Y. Chew, Itay Chowers, Steven Clarke, Catherine A. Cukras, C. Delcourt, M. Delyfer, A. D. den Hollander, Sascha Fauser, R. P. Finger, P. Gabrielle, Jiru Han, L. Hodgson, R. Hogg, F. Holz, C. Hoyng, Himeesh Kumar, E. Lad, Aaron Y. Lee, U. Luhmann, M. Mauschitz, A. J. McKnight, S. McLenachan, Aniket Mishra, Ismail Moghul, Luz D. Orozco, Danuta M. Sampson, L. W. Scott, V. Sitnilska, Scott Song, A. Stockwell, A. Swaroop, J. Terheyden, Liran Tiosano, A. Tufail, B. Yaspan, Alice Pébay, Erica L. Fletcher, Robyn H. Guymer, Melanie Bahlo   +48 more
semanticscholar   +2 more sources

Microperimetry to predict disease progression in eyes at high risk of age‐related macular degeneration disease: The PREVISION study

Acta Ophthalmologica, Volume 101, Issue 2, Page e135-e142, March 2023., 2023
Abstract Purpose The aim of the present study was to determine whether microperimetric parameters could predict the progression of an eye at high risk of age‐related macular degeneration (AMD) at 24 months. Methods We conducted a multicentric prospective non‐comparative open‐label study including patients with one eye in stage 4 of the Age‐Related Eye ...
Laurent Kodjikian, Catherine Creuzot‐Garcher, Jean‐François Korobelnik, Ramin Tadayoni, Ivan Delafoy, Cécilia Leal, Lorraine Bernard, Evelyne Decullier, Laure Huot, Thibaud Mathis   +9 more
wiley   +1 more source

Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina

Journal of Extracellular Vesicles, Volume 11, Issue 12, December 2022., 2022
Abstract Age‐related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis. Here we use AMD patient‐specific RPE cells with the Complement Factor H Y402H high‐risk polymorphism to perform a comprehensive analysis of ...
Marzena Kurzawa‐Akanbi, Phillip Whitfield, Florence Burté, Pietro Maria Bertelli, Varun Pathak, Mary Doherty, Birthe Hilgen, Lina Gliaudelytė, Mark Platt, Rachel Queen, Jonathan Coxhead, Andrew Porter, Maria Öberg, Daniela Fabrikova, Tracey Davey, Chia Shyan Beh, Maria Georgiou, Joseph Collin, Veronika Boczonadi, Anetta Härtlova, Michael Taggart, Jumana Al‐Aama, Viktor I Korolchuk, Christopher M Morris, Jasenka Guduric‐Fuchs, David H Steel, Reinhold J Medina, Lyle Armstrong, Majlinda Lako   +28 more
wiley   +1 more source