Results 51 to 60 of about 47,296 (185)

Microperimetry to predict disease progression in eyes at high risk of age‐related macular degeneration disease: The PREVISION study

Acta Ophthalmologica, Volume 101, Issue 2, Page e135-e142, March 2023., 2023
Abstract Purpose The aim of the present study was to determine whether microperimetric parameters could predict the progression of an eye at high risk of age‐related macular degeneration (AMD) at 24 months. Methods We conducted a multicentric prospective non‐comparative open‐label study including patients with one eye in stage 4 of the Age‐Related Eye ...
Laurent Kodjikian, Catherine Creuzot‐Garcher, Jean‐François Korobelnik, Ramin Tadayoni, Ivan Delafoy, Cécilia Leal, Lorraine Bernard, Evelyne Decullier, Laure Huot, Thibaud Mathis   +9 more
wiley   +1 more source

Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina

Journal of Extracellular Vesicles, Volume 11, Issue 12, December 2022., 2022
Abstract Age‐related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis. Here we use AMD patient‐specific RPE cells with the Complement Factor H Y402H high‐risk polymorphism to perform a comprehensive analysis of ...
Marzena Kurzawa‐Akanbi, Phillip Whitfield, Florence Burté, Pietro Maria Bertelli, Varun Pathak, Mary Doherty, Birthe Hilgen, Lina Gliaudelytė, Mark Platt, Rachel Queen, Jonathan Coxhead, Andrew Porter, Maria Öberg, Daniela Fabrikova, Tracey Davey, Chia Shyan Beh, Maria Georgiou, Joseph Collin, Veronika Boczonadi, Anetta Härtlova, Michael Taggart, Jumana Al‐Aama, Viktor I Korolchuk, Christopher M Morris, Jasenka Guduric‐Fuchs, David H Steel, Reinhold J Medina, Lyle Armstrong, Majlinda Lako   +28 more
wiley   +1 more source

Retinal vascular flow and choroidal thickness in eyes with early age-related macular degeneration with reticular pseudodrusen

BMC Ophthalmology, 2018
Background To investigate the characteristics of retinal vessels and retinal thickness in eyes with early age-related macular degeneration (AMD) with or without reticular pseudodrusen. Methods We retrospectively evaluated the clinical history and optical
So Min Ahn, Suk Yeon Lee, Soon-Young Hwang, Seong-Woo Kim, Jaeryung Oh, Cheolmin Yun   +5 more
doaj   +1 more source

An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration. [PDF]

, 2018
Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of ...
Bailey, C., Binns, A. M., Margrain, T. H., Robinson, D. G.   +3 more
core   +3 more sources

Age‐related macular degeneration and myeloproliferative neoplasms – A common pathway

Acta Ophthalmologica, Volume 100, Issue S271, Page 3-35, October 2022., 2022
Summary Dansk Resumé (Danish summary) Aldersrelateret makuladegeneration (AMD) er den hyppigste årsag til uopretteligt synstab og blindhed i højindkomstlande. Det er en progredierende nethindesygdom som gradvist fører til ødelæggelse af de celler som er ansvarlige for vores centralsyn. De tidlige stadier er ofte asymptomatiske, imens senstadie AMD, som
Charlotte Liisborg
wiley   +1 more source

Subretinal drusenoid deposits: An update

Taiwan Journal of Ophthalmology, 2022
A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs),
Manuel Monge, Adriana Araya, Lihteh Wu
doaj   +1 more source

Evaluation of coronary artery disease as a risk factor for reticular pseudodrusen [PDF]

, 2017
Purpose: Reticular pseudodrusen (RPD) are a risk factor for late age-related macular degeneration (AMD). Associations between RPD and coronary artery disease (CAD) have been reported from small case-control studies.
Baljean Dhillon, Buitendijk, Chan, Cheng, Cymerman, David E Newby, Domalpally, Edwin JR van Beek, Emanuele Trucco, Enrico Pellegrini, Finger, Frank Kee, Gareth J McKay, Gavin Robertson, Gliem, Gliem, Ian S Young, Leisy, Michelle C Williams, Nicola B Quinn, Pellegrini, Rachel V McCarter, Rastogi, Ruth E Hogg, Tom J MacGillivray, Tunde Peto, Usha Chakravarthy, Wu   +27 more
core   +4 more sources

Point‐of‐care tools to support optometric care provision to people with age‐related macular degeneration: A randomised, placebo‐controlled trial

Ophthalmic and Physiological Optics, Volume 42, Issue 4, Page 814-827, July 2022., 2022
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of vision impairment. This randomised placebo‐controlled trial investigated whether point‐of‐care tools can improve optometrists' AMD knowledge and/or care provision. Methods Australian optometrists (n = 31) completed a demographics survey and theoretical AMD case study multiple‐
Sena A Gocuk, Allison M McKendrick, Laura E Downie   +2 more
wiley   +1 more source

In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]

, 2017
Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David, Farsiu, Sina, Garzel, Laura, Munevar, Christian, Roberts, Jeffrey, Thomasy, Sara, Tieu, Eric, Wong, Brittany, Yiu, Glenn   +8 more
core   +2 more sources

Clinical and Multimodal Imaging Features of Subretinal Drusenoid Deposits [PDF]

, 2021
Purpose: To describe the multimodal imaging (MMI) features of subretinal drusenoid deposits (SDD) in Indian population. Methods: Patients diagnosed to have SDD from January 2016 to December 2018 at our tertiary care center were recruited.
K. Padhy, Srikanta, Kumar, Vinod, Kumawat, Devesh   +2 more
core   +3 more sources