Results 61 to 70 of about 18,397 (221)

Thalamic reticular nucleus in the pathophysiology of schizophrenia

Neural Regeneration Research
Abstract Mechanistic analyses on schizophrenia have traditionally focused on corticolimbic structures such as the prefrontal cortex, hippocampus, and amygdala, given their established roles in cognition. However, the thalamus, a critical hub that interconnects these regions, has garnered comparatively less attention.
Gonzalo Flores, David J. Apam-Castillejos, Hannaford Edwards, Victor M. Magdaleno-Madrigal, Juan Nacher, Hiram Tendilla-Beltrán, Lalit K. Srivastava   +6 more
openaire   +2 more sources

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

A thalamic reticular networking model of consciousness [PDF]

, 2010
[Background]: It is reasonable to consider the thalamus a primary candidate for the location of consciousness, given that the thalamus has been referred to as the gateway of nearly all sensory inputs to the corresponding cortical areas. Interestingly, in
Byoung-Kyong Min, VA Lamme, S Dehaene, S Zeki, EG Jones, JD Schmahmann, JD Schmahmann, EG Jones, CJ Shatz, H Kennedy, DN Pandya, TA Hackett, MM Mesulam, EG Jones, EG Jones, IA Ilinsky, M Steriade, UB Schambra, S Wang, Y Shu, M Steriade, GB Lundkvist, XJ Wang, EG Jones, JM Fuster, DA McCormick, G van Luijtelaar, RK Berdiev, CT Yen, CR Houser, D Pinault, D Pinault, L Domich, DA McCormick, M Steriade, G Avanzini, MA Long, M Xu, C Mulle, M Steriade, J Szabadics, CS Herrmann, CS Herrmann, AK Engel, P Fries, M Steriade, JR Huguenard, DA McCormick, JA Hartings, SM Sherman, G Marini, T Bal, M Steriade, M Steriade, D Contreras, RB Mistry, SM Sherman, M Deschenes, FS Lo, M Steriade, SM Sherman, EJ Ramcharan, TG Weyand, DL Schacter, M Conley, JW Crabtree, DA Lozsadi, SM Sherman, YT So, JB Mattingley, ZI Nanobashvili, DJ Uhlrich, V Henkel, K Imai, G Winterer, YA Bayazit, P Nencini, R Bachner-Melman, JR Park, R Desimone, J Stehberg, F Crick, SL Bressler, JM Fuster, DE Rumelhart, CM Gray, JM Fuster, W James, S Fecteau, DJ Barraclough, F Manes, S van Gaal, JA Johnson, MA Vanderhasselt, TJ Buschman, S Grimault, P Malhotra, S Yantis, S Itami, AC Nobre, P Andrade, P Bartolomeo, MI Posner, EA Maylor, S Yantis, XJ Yu, DO Hebb, J Duncan, RA Weddell, VC Raos, SM Lee, C Bucherelli, PA McCormick, D Pinault, C Koch, B Libet, S Bodovitz, HL Roediger, RT Watson, VA Lamme, S Zeki, HC Lau, L Weiskrantz, NR McFarland, C Asanuma, M Sidibe, JM Fuster, PD Cheney   +127 more
core   +3 more sources

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Analysis of the Neuron Dynamics in Thalamic Reticular Nucleus by a Reduced Model

Frontiers in Computational Neuroscience, 2021
Strategically located between the thalamus and the cortex, the inhibitory thalamic reticular nucleus (TRN) is a hub to regulate selective attention during wakefulness and control the thalamic and cortical oscillations during sleep.
Chaoming Wang, Chaoming Wang, Chaoming Wang, Shangyang Li, Si Wu, Si Wu   +5 more
doaj   +1 more source

The what, which, when, why and who of Off responses in the auditory system

The Journal of Physiology, EarlyView.
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley   +1 more source

Dynamics of action potential initiation in the GABAergic thalamic reticular nucleus in vivo. [PDF]

PLoS ONE, 2012
Understanding the neural mechanisms of action potential generation is critical to establish the way neural circuits generate and coordinate activity.
Fabián Muñoz, Pablo Fuentealba
doaj   +1 more source

Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist [PDF]

, 1990
1. Intracellular microelectrodes were used to obtain recordings from neurons in layer II/III of rat frontal cortex. A bipolar electrode positioned in layer IV of the neocortex was used to evoke postsynaptic potentials.
Hablitz, John H., Sutor, Bernd
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Stability or Plasticity? – A Hierarchical Allostatic Regulation Model of Medial Prefrontal Cortex Function for Social Valuation

Frontiers in Neuroscience, 2020
The medial prefrontal cortex (mPFC) has long been recognized as the key component of the neurocircuitry involved in various social as well as non-social behaviors, however, little is known regarding the organizing principle of distinctive subregions in ...
Hackjin Kim
doaj   +1 more source