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Clinical Applicability of Reticulated Platelets
Clinica Chimica Acta, 2015Reticulated platelets (RPs), immature platelets newly released from the bone marrow into the circulation, have a high content of ribonucleic acid and are larger and more active in thrombus formation.This review compiles articles that evaluated RP in order to establish their clinical significance.RPs increase when platelet production rises and decrease ...
Luci Maria SantAna Dusse
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Reticulated Platelets: Analytical Aspects and Clinical Utility
Clinical Chemistry and Laboratory Medicine, 2014Reticulated platelets are immature platelets circulating in blood; they reflect the activity of megakaryopoiesis in the bone marrow. Therefore, they can be used as a non-invasive test in patients with thrombocytopenia in various clinical conditions. The preferred method of analysis is by flow cytometry.
Johannes J M L Hoffmann
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Automated Measurement of Reticulated Platelets in Estimating Thrombopoiesis
European Journal of Haematology, 1995Abstract: We described a fully automated measurement of reticulated platelets using a fluorescent dye, auramine O, and a reticulocyte counter, the R‐3000, equipped with special software. Reproducibility and linearity were shown to be good. In the normal subjects studied (n = 60), the mean value for reticulated platelets was 0.98% ± 0.41% and the mean ...
Kiyoaki Watanabe +2 more
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Quantitation of Reticulated Platelets: Methodology and Clinical Application
British Journal of Haematology, 1995Summary. A practical technique for the preparation and analysis of reticulated platelets is described. The use of fixed platelet‐rich plasma has given optimal results and sample stability. This technique has detected consumptive causes of a platelet count <80 × 109/1 with a positive predictive value of 96% and negative predictive value of 100%. The
E M, Richards, T P, Baglin
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Research in Veterinary Science, 2012 Reticulated platelets are considered as marker for bone marrow thrombopoiesis. The aim of the study was evaluate the role of reticulated platelets as markers of thrombopoiesis in dogs.
Regina K Takahira
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Flow Cytometric Analysis of Reticulated Platelets
Current Protocols in Cytometry, 2001AbstractFlow Cytometric Analysis of Reticulated Platelets (G. Matic, G. Rothe, and G. Schmitz, University of Regensburg, Regensburg, Germany). In the last several years, flow cytometry has emerged as one of the tools of choice in evaluation of platelets.
G B, Matic, G, Rothe, G, Schmitz
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Evaluation of reticulated platelets in dogs
Comparative Haematology International, 1998Reticulated platelets are immature platelets that have increased ribonucleic acid content. Reticulated platelets were evaluated in the blood of 20 healthy non-thrombocytopenic dogs and 45 thrombocytopenic dogs to determine if the assay could be used as a non-invasive measure of thrombopoiesis.
D. J. Weiss, E. Townsend
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Functional Analyses of Reticulated Platelets
The FASEB Journal, 2017Objective To isolate reticulated platelets from platelet rich plasma and consequently assess functional reactivity and mRNA content. Introduction The platelet population is a heterogeneous mix of various sub‐populations, potentially ...
Melissa Hayman +3 more
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Reticulated platelets predict platelet count recovery following chemotherapy
Transfusion, 2002BACKGROUND:A laboratory measure that predicted the timing of platelet recovery after chemotherapy could guide prophylactic platelet transfusion. Reticulated platelets (RPs) are the youngest circulating platelets; an increased percentage of RPs is diagnostic of increased marrow platelet production, such as seen with idiopathic thrombocytopenic purpura ...
Chao, Wang +3 more
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Characterization of surface antigens of reticulated immature platelets
Journal of Thrombosis and Thrombolysis, 2017Reticulated platelets (RPs) are immature platelets with high dense granules content and a residual amount of megakaryocyte-derived of mRNA. Increased level of RPs has been found to be an independent predictor of cardiovascular ischemic events, and has been associated with impaired response to various anti-platelet drugs. The study aimed to characterize
Adi Lador +5 more
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