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Reticulated Platelets following Acute Blood Loss
British Journal of Haematology, 1969Summary. This report describes a previously unreported type of platelet released into the peripheral blood of dogs following acute blood loss. These cells display coarse, punctate condensations (reticulum) when stained supravitally with new methylene blue, and are probably analogous to reticulated erythrocytes. Both types of reticulated cells occur in
M, Ingram, A, Coopersmith
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Reticulated platelet counts in the assessment of thrombocytopenic disorders
Acta Paediatrica, 1998Reticulated platelets (RP) are the youngest platelets in the circulation and can be measured by analysing the RNA content of platelets from whole blood or platelet‐rich plasma by flow cytometry. Increased RP are indicative of increased production of platelets.
B R, Saxon +3 more
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Thrombosis and Haemostasis, 2016
SummaryReticulated platelets are associated with impaired antiplatelet response to thienopyridines. It is uncertain whether this interaction is caused by a decreased drug exposure due to high platelet turnover reflected by elevated levels of reticulated platelets or by intrinsic properties of reticulated platelets.
Stratz, Christian +8 more
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SummaryReticulated platelets are associated with impaired antiplatelet response to thienopyridines. It is uncertain whether this interaction is caused by a decreased drug exposure due to high platelet turnover reflected by elevated levels of reticulated platelets or by intrinsic properties of reticulated platelets.
Stratz, Christian +8 more
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Combined accurate platelet enumeration and reticulated platelet determination by flow cytometry
Cytometry Part B: Clinical Cytometry, 2015BackgroundDiagnosing the cause of thrombocytopenia often requires a bone marrow aspiration or biopsy, an invasive procedure. Reticulated platelets (RP) are immature RNA containing platelets, accurate RP enumeration has yet to be achieved, partially due to the lack of a robust reference method.Goal: To refine previous work and gating strategies ...
Benjamin D, Hedley +6 more
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Reticulated platelets and antiplatelet therapy response in diabetic patients
Journal of Thrombosis and Thrombolysis, 2015Increased platelet turnover and high level of reticulated platelets are associated with low response to antiplatelet therapy in diabetes mellitus type 2. This study evaluated association between percentage of reticulated platelets (%RP) and the response to antiplatelet therapy in patients with type 2 diabetes mellitus (T2DM).
Romana, Mijovic +5 more
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Reticulated platelets: How to assess them?
Clinica Chimica Acta, 2013Letícia Gonçalves, Freitas +2 more
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[Comparison of testing methods for reticulated platelets].
Zhonghua yi xue za zhi, 2013To compare the accuracy, stability and sample cross-contamination of two independent methods of detecting the percentage of reticulated platelets in peripheral blood and establish a local normal reference range so as to provide methodological rationales in clinical laboratory.The percentages of reticulated platelets in peripheral blood of a healthy ...
Yao-ling, Luo +2 more
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Experimental hematology, 1995
In both mice and humans, a subset of platelets can be identified that shows increased labeling with nucleic acid-specific fluorescent dyes, such as thiazole orange. Termed "reticulated platelets," they have been postulated to be platelets that have recently entered the circulation.
K A, Ault, C, Knowles
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In both mice and humans, a subset of platelets can be identified that shows increased labeling with nucleic acid-specific fluorescent dyes, such as thiazole orange. Termed "reticulated platelets," they have been postulated to be platelets that have recently entered the circulation.
K A, Ault, C, Knowles
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[Reticulated platelet and its clinical significance].
Rinsho byori. The Japanese journal of clinical pathology, 2002Reticulated platelets (RP) retain some residual mRNA in their cytoplasm and are thought to be the most recently produced platelets in circulation. They can be visualized on a blood film with new methylene blue staining. RP is a flow cytometric assay utilizing a fluorescent dye, either thiazole orange or auramine O.
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