Results 101 to 110 of about 42,523 (238)
The PNH French Working Group Experience: Building a Strong Network of Cytometrists
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon +9 more
wiley +1 more source
ABSTRACT Introduction We investigated the stability and accuracy of platelets with MgSO4 and compared the results of blood counts between MgSO4 and K2EDTA. Methods Platelet stability as a function of time was assessed on the XN Sysmex analyzer by comparing the percentage deviation to the desirable bias of the EFLM.
Michel Soulard +4 more
wiley +1 more source
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang +9 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang +18 more
wiley +1 more source
How We Use Reticulocyte Parameters in Workup and Management of Pediatric Hematologic Diseases
Emilia Parodi +3 more
doaj +1 more source
ABSTRACT Lead poisoning should be considered in patients presenting with unexplained anemia and abdominal pain, even without clear environmental or occupational exposure. Recognizing classic signs such as Burton's line and basophilic stippling enables timely diagnosis and effective chelation therapy.
Jennifer Eichler +2 more
wiley +1 more source
From Hemolysis to Lupus: A Case of Evans Syndrome Revealing Systemic Autoimmunity
ABSTRACT Evans syndrome (ES), the coexistence of autoimmune hemolytic anemia and immune thrombocytopenia, can unmask systemic autoimmune disease. We report a 30‐year‐old woman who presented with fatigue, jaundice, pallor, and mucocutaneous bleeding.
Biruk T. Mengistie +6 more
wiley +1 more source

