Three Faces of Self-Destruction: A Case Series of Warm, Cold, and Mixed Autoimmune Hemolytic Anemia. [PDF]
K H +6 more
europepmc +1 more source
ABSTRACT Background Sickle cell anemia (SCA) is highly prevalent in Central Africa. This disease causes severe manifestations in children, requiring treatment. Hydroxyurea (HU) is currently the most effective treatment for SCA. We evaluated the use of HU in children living in rural Central Africa.
Gloire Mbayabo +9 more
wiley +1 more source
The Hydroxyurea Absorption Phenotype: A Key PK/PD Determinant in Sickle Cell Disease Treatment. [PDF]
Sabo AN, Nazon C, Paillard C, Kemmel V.
europepmc +1 more source
Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha ( Withania somnifera )
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
Unmasking a High-Grade Malignant Neoplasm: A Rare Case of Small Bowel Melanoma. [PDF]
Vemulakonda LA, Reddi D, Liu Y.
europepmc +1 more source
Primary rib haemangiosarcoma in two dogs
Abstract Primary rib haemangiosarcoma is an uncommon neoplasm, with only 24 cases reported since 1974. We describe the clinical presentation, diagnostic findings, and outcomes of two dogs with this condition. One dog was younger than 4 years old. Clinical signs included a palpable thoracic mass, lethargy, hyporexia, dyspnoea, pale mucous membranes and ...
Jocosa T. Yasenchack +4 more
wiley +1 more source
Use of Human Intravenous Immunoglobulin Therapy in Two Dogs with Non-Neoplastic Bone Marrow Disorders Refractory to Immunosuppressive Therapy. [PDF]
Kim EJ, Han HJ.
europepmc +1 more source
Pyometra in an African wild dog (Lycaon pictus)
Abstract Reports of pyometra in wild canids such as African wild dogs remain scarce. Management of pyometra in geriatric individuals with concurrent anaemia presents a distinctive clinical challenge. A 16.1 kg rescued geriatric female African wild dog (Lycaon pictus) presented to Greens Zoological Rescue and Rehabilitation Centre, Jamnagar, with ...
Nitin Tambe +4 more
wiley +1 more source
Machine learning-based genome-wide association analysis to construct a clinical decision model for severe neonatal jaundice. [PDF]
Ma H +7 more
europepmc +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source

