Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Natural History of Chronic Kidney Disease in Sickle Cell Disease
American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley +1 more source
American Journal of Hematology, Volume 101, Issue 7, Page 1597-1604, July 2026.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
The Role of Reticulocyte-Derived Parameters in the Detection of Iron-Restricted Erythropoiesis in the Elderly. [PDF]
Diagnostics (Basel)Urrechaga E, Fernández M.
europepmc +1 more source
Reply to letter to the editor in response to: “Carbon monoxide to ‘simulate altitude’”
Experimental Physiology, EarlyView.
Simone Villanova +3 more
wiley +1 more source
A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia
American Journal of Hematology, Volume 101, Issue 7, Page 1706-1716, July 2026.ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger +14 more
wiley +1 more source
The Impact of Bacterial Infections on Delayed Hematopoietic Recovery in Patients with Acute Leukemia After Induction and Consolidation Therapy. [PDF]
J Clin MedGawronski K +6 more
europepmc +1 more source
How We Use Reticulocyte Parameters in Workup and Management of Pediatric Hematologic Diseases
Frontiers in Pediatrics, 2020 Emilia Parodi +3 more
doaj +1 more source
Alterations in Erythrocyte and Platelet Characteristics Are Poor Indicators of Metastasis in Dogs with Carcinoma or Sarcoma: A Preliminary Study. [PDF]
Vet SciMulder AA, Goddard A, Pazzi P.
europepmc +1 more source