High-performance liquid chromatography screening reveals HbS/β+-thalassemia double heterozygosity as a pediatric muscular dystrophy mimic. [PDF]
López-Medina C +5 more
europepmc +1 more source
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed +11 more
wiley +1 more source
In-depth analysis of osmotic gradient ektacytometry parameters across different genotypes in hereditary spherocytosis. [PDF]
de Wilde JRA +9 more
europepmc +1 more source
Diagnosis and management of neutropenia in adults: Expert guidance
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte +5 more
wiley +1 more source
Risk factors underlying brain structure change rate in cognitive decline: Results from genomewide and phenomewide investigations. [PDF]
Jin Y +3 more
europepmc +1 more source
This study shows that sickle cell disease patients have elevated high‐sensitivity cardiac troponin I (hs‐cTnI) that is not considered clinically significant but are outside of the normal range. Elevated hs‐cTnI was associated with low haemoglobin and a history of heart failure.
Abdelrhman Mohammed +3 more
wiley +1 more source
Hematological, inflammatory, and hypoxia-responsive adaptations to 18-day normobaric live high-train low training in elite rowers. [PDF]
Kasperska A +6 more
europepmc +1 more source
Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking +6 more
wiley +1 more source
Erythropoietic indices in asthma patients on controller medications: a comparative analysis. [PDF]
Abdullahi L +4 more
europepmc +1 more source
ABSTRACT Anemia of chronic disease (ACD), also referred to as anemia of inflammation, is a prevalent and clinically significant complication of chronic infection, autoimmune disease, malignancy, and chronic kidney disease. It is characterized by inflammation‐driven iron sequestration, impaired erythropoietin (EPO) production and signaling, and ...
Mohammed Abdulgayoom +5 more
wiley +1 more source

