Results 211 to 220 of about 48,191 (295)

Reticulated Platelets and an Optimal Model for Differentiating Thrombocytopenia Etiologies

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Objectives This study aimed to investigate the clinical value of reticulated platelets (RtcPLT) percentage derived from an automated hematology analyzer in differentiating thrombocytopenia due to peripheral etiology from decreased bone marrow production (BME). In addition, a secondary objective was to establish specific reference intervals for
Tung Thanh Tran, Quyen Ngoc Truong, Hong Phuoc Mac, Thang Thanh Phan, Tai Chau Quach, Son Truong Nguyen   +5 more
wiley   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Low reticulocyte count at infusion is a risk factor for high-grade cytokine release syndrome in chimeric antigen receptor T cell therapy. [PDF]

Int J Hematol
Tashiro Y, Jo T, Kitawaki T, Yoshinaga N, Sakamoto T, Shirakawa K, Kanda J, Nishikori M, Yamashita K, Nagao M, Takaori-Kondo A, Arai Y.   +11 more
europepmc   +1 more source

Post‐Transfusion Purpura: A Clinical Case With Alveolar Haemorrhage

Respirology Case Reports, Volume 14, Issue 6, June 2026.
We report a case of post‐transfusion thrombocytopenic purpura and alveolar haemorrhage in a woman after knee replacement surgery, occurring 7 days after transfusion of 20 mL of blood. This case was successfully treated with therapeutic plasma exchange and intravenous immunoglobulin.
Yordanka Yamakova, Aleksandar Pisanchev, Aleksandar Farfarov, Rosen Petkov   +3 more
wiley   +1 more source

Mechanistic Consequences of Piezo1 Gain-of-Function Variants for Decreased Red Cell Survival in Hereditary Xerocytosis. [PDF]

Am J Hematol
Makhro A, Huisjes R, Seiler E, Qiao M, Bartels M, Hegemann I, Eppenberger P, Bender N, Dorn I, Bogdanova A, van Wijk R, Kaestner L.   +11 more
europepmc   +1 more source

Ten-year clinical course of familial lecithin-cholesterol acyltransferase deficiency caused by Cys74Tyr mutation leading to dialysis and multiple systemic complications: a case report. [PDF]

CEN Case Rep
Yamazaki T, Naito S, Sakurabayashi S, Sano K, Abe T, Kamata M, Aoyama T, Takeuchi Y.   +7 more
europepmc   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Vitamin B12 Deficiency-Associated Pseudo-Thrombotic Microangiopathy in a Patient on Longstanding Oral B12 Supplementation. [PDF]

Clin Case Rep
Bertucci HK, Moy BM, Stein R.
europepmc   +1 more source

A genetic risk score based on BCL11A and HBS1L‐MYB variants predicts clinical severity in Brazilian sickle cell anaemia patients

British Journal of Haematology, Volume 208, Issue 6, Page 2203-2211, June 2026.
Summary Individuals with sickle cell anaemia (SCA) exhibit significant clinical heterogeneity influenced by several factors, especially fetal haemoglobin (HbF) levels. Variations in adult HbF levels are partly explained by the co‐inheritance of genetic variants that regulate globin expression.
Gabriela S. Arcanjo, Alexsandro P. Silva, Madi V. Diniz, Igor F. Domingos, Diego A. Pereira‐Martins, Amanda B. Araújo, Talita S. S. França, Ana C. Anjos, Aderson S. Araujo, Edis Belini‐Junior, Sara T. O. Saad, Fernando F. Costa, Antonio R. Lucena‐Araujo, Marcos André C. Bezerra   +13 more
wiley   +1 more source