Results 31 to 40 of about 28,723 (221)

Red cell distribution width and reticulocyte hemoglobin content as predictors of iron depletion in children with cyanotic congenital heart disease [PDF]

Clinical and Experimental Pediatrics
Background Iron-deficiency anemia is challenging to diagnose in patients with cyanotic congenital heart disease (CCHD) because of the high hemoglobin concentration as a compensatory mechanism for cyanosis.
Hanyudh Prichayudh, Kanhatai Chiengthong, Khwaunrat Whaidee, Navaporn Phiphattanatikanunt, Vidhavas La-orkhun, Pornthep Lertsapcharoen   +5 more
doaj   +1 more source

Reticulocyte and erythrocyte hypochromia markers in detection of iron deficiency in adolescent female athletes

Biology of Sport, 2017
The aim of this study was to analyse the effectiveness of new haematology parameters related to reticulocytes and mature red blood cells to differentiate pre latent and latent iron deficiency.
J Malczewska-Lenczowska, J Orysiak, B Szczepańska, D Turowski, K Burkhard-Jagodzińska, J Gajewski   +5 more
doaj   +1 more source

Acute and Chronic Dosing of a High-Affinity Rat/Mouse Chimeric Transferrin Receptor Antibody in Mice

Pharmaceutics, 2020
Non-invasive brain delivery of neurotherapeutics is challenging due to the blood-brain barrier. The revived interest in transferrin receptor antibodies (TfRMAbs) as brain drug-delivery vectors has revealed the effect of dosing regimen, valency, and ...
Demi M. Castellanos, Jiahong Sun, Joshua Yang, Weijun Ou, Alexander C. Zambon, William M. Pardridge, Rachita K. Sumbria   +6 more
doaj   +1 more source

The Presence and Percentage of Circulating Nucleated Red Blood Cells Reveal Distinct Characteristics in Adults With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco, Ivan Lerner, Auria Godard, Luc Darnige, Laure Joseph, Wassim El Nemer, Geoffrey Cheminet, Jean‐Benoit Arlet   +7 more
wiley   +1 more source

Identification of F-reticulocytes by two-stage fluorescence image cytometry.

, 1996
Precise determination of reticulocytes (young red blood cells) containing fetal hemoglobin (Hb F), F-reticulocytes, is important for assessment of the efficacy of drugs such as hydroxyurea and butyrate in elevating the levels of Hb F in patients with ...
K Ohene-Frempong, K Horiuchi, M L Osterhout   +2 more
core   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation

American Journal of Hematology, EarlyView.
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard, Tianjian Lin, Nana A. Peterson, Rebekah C. Gullberg, Yann Le Guen, Jasmine Moshiri, John G. Doench, Elizabeth S. Egan   +7 more
wiley   +1 more source

% reticulocytes (RETs) and % micronucleated reticulocytes (MN-RETs) in peripheral blood in in vivo micronucleus study in rats.

, 2019
% reticulocytes (RETs) and % micronucleated reticulocytes (MN-RETs) in peripheral blood in in vivo micronucleus study in rats.
Sophie Lachau-Durand (1834051), Bas-jan van der Leede (6236453), Ann Lampo (6236459), Lieve Lammens (6236450), Graham Bailey (2398456), Marc Engelen (149627), Jacky Van Gompel (6236456)   +6 more
core   +1 more source

Red Blood Cell Surface Proteins and Cryopreservation for Tracking Altered Erythropoiesis

Drug Testing and Analysis, EarlyView.
Recombinant human erythropoietin altered red blood cell surface protein expression, but responses were inconsistent and accompanied by substantial baseline variability. Although cryopreservation reduced analytical variability, it did not improve biomarker performance, indicating limited utility for detecting altered erythropoiesis. ABSTRACT The present
Martin Thomassen, Thomas Bonne, Jonathan Graae, Sophie Møller, Ylva Hellsten, Henrik Sørensen, Nikolai B. Nordsborg, Jacob Bejder   +7 more
wiley   +1 more source

Rodent Malaria Erythrocyte Preference Assessment by an Ex Vivo Tropism Assay

Frontiers in Cellular and Infection Microbiology, 2021
Circulating red blood cells consist of young erythrocytes (early and late reticulocytes) and mature erythrocytes (normocytes). The human malaria parasites, Plasmodium falciparum and P.
Yew Wai Leong, Yew Wai Leong, Yew Wai Leong, Erica Qian Hui Lee, Laurent Rénia, Laurent Rénia, Laurent Rénia, Benoit Malleret, Benoit Malleret   +8 more
doaj   +1 more source