Results 41 to 50 of about 376,903 (143)

Stress Management: How the Endoplasmic Reticulum Mitigates Protein Misfolding and Oxidative Stress by the Dual Role of Glutathione Peroxidase 8

Biomolecules
The endoplasmic reticulum mediates essential processes such as protein folding, transport, and post-translational modifications. Disruptions in endoplasmic reticulum function can lead to the accumulation of unfolded or misfolded proteins, initiating ...
Yong Yang, Hao Peng, Danni Meng, Zizhu Fa, Chen Yao, Xinyu Lin, Joel Schick, Xiang Jin   +7 more
doaj   +1 more source

Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum

Cell Reports, 2019
Summary: Calcium homeostasis in the lumen of the endoplasmic reticulum is required for correct processing and trafficking of transmembrane proteins, and defects in protein trafficking can impinge on cell signaling pathways. We show here that mutations in
Annabelle Suisse, Jessica E. Treisman
doaj   +1 more source

Direct observation of molecular arrays in the organized smooth endoplasmic reticulum

BMC Cell Biology, 2009
Background Tubules and sheets of endoplasmic reticulum perform different functions and undergo inter-conversion during different stages of the cell cycle.
Korkhov Vladimir M, Zuber Benoît
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Protein kinase R-like endoplasmic reticulum kinase pathway and diabetic kidney disease

Linchuang shenzangbing zazhi, 2020
Endoplasmic reticulum stress is closely related to the occurrence and development of diabetic kidney disease.As an important signaling pathway induced by endoplasmic reticulum stress,protein kinase R-like endoplasmic reticulum kinase(PERK)pathway can ...
庞欣欣, 彭紫凝, 邢玉凤, 张雅歌, 石秀杰, 韩佳瑞   +5 more
doaj  

Experimental determination of the membrane topology of the Plasmodium protease Plasmepsin V.

PLoS ONE, 2015
The malaria parasite exports hundreds of proteins into its host cell. The majority of exported proteins contain a Host-Targeting motif (also known as a Plasmodium export element) that directs them for export.
Sarah J Tarr, Andrew R Osborne
doaj   +1 more source

The clinical significance of endoplasmic reticulum stress related genes in non-small cell lung cancer and analysis of single nucleotide polymorphism for CAV1

Frontiers in Molecular Biosciences
In recent years, protein homeostasis imbalance caused by endoplasmic reticulum stress has become a major hallmark of cancer. Studies have shown that endoplasmic reticulum stress is closely related to the occurrence, development, and drug resistance of ...
Shuang Li, Junting Chen, Baosen Zhou
doaj   +1 more source

Sarcoplasmic reticulum

Archives of Biochemistry and Biophysics, 1971
A. Pucell, A. Martonosi
openaire   +2 more sources

Research hotspots and frontiers of endoplasmic reticulum in glomerular podocytes: a bibliometric and visual analysis from 2005 to 2023

Frontiers in Pharmacology
BackgroundThe glomerular podocyte endoplasmic reticulum is a critical component in renal function, yet its research landscape is not fully understood.
Wang Junli, Hao Zhihong, Wang Lina, Ou Qiaoqun, Qu Jing, Hu Jiaqi, Shengyou Yu, Shengyou Yu, Shengyou Yu   +8 more
doaj   +1 more source

Sarcoplasmic reticulum

Archives of Biochemistry and Biophysics, 1969
A. Martonosi, R.A. Halpin
openaire   +2 more sources

Unfolded protein response in endoplasmic reticulum stress associated with retinal degenerative diseases: A promising therapeutic target

Neural Regeneration Research
The unfolded protein response is a cellular pathway activated to maintain proteostasis and prevent cell death when the endoplasmic reticulum is overwhelmed by unfolded proteins.
Hongbing Zhang, Yalin Mu, Hongsong Li, Xiaogang Li   +3 more
doaj   +1 more source