Results 151 to 160 of about 448,808 (241)

Cholinesterase in the retina [PDF]

The Journal of Physiology, 1953
openaire   +3 more sources

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis

Animal Models and Experimental Medicine, EarlyView.
The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome, Ilva D. Rupenthal, Rachael L. Niederer, Odunayo O. Mugisho   +3 more
wiley   +1 more source

Spatial transcriptomics reveals regionally altered gene expression that drives retinal degeneration. [PDF]

Commun Biol
Schumann U, Liu L, Aggio-Bruce R, Cioanca AV, Shariev A, Madigan MC, Valter K, Wen J, Natoli R.   +8 more
europepmc   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

A Window to the Brain-The Enduring Impact of Vision Research. [PDF]

Brain Sci
Ayoub G.
europepmc   +1 more source

Spontaneously Diabetic Torii Fatty Rat Shows Early Stage of Diabetic Retinopathy Characterized by Capillary Changes and Inflammation. [PDF]

J Diabetes Res
Kikuchi K, Murata M, Kageyama Y, Shinohara M, Sasase T, Noda K, Ishida S.   +6 more
europepmc   +1 more source

The Impact of Allogeneic Hematopoietic Stem Cell Transplantation on Sickle Cell Retinopathy and Maculopathy: A Prospective, Observational Study

American Journal of Hematology, EarlyView.
Rajani P. Brandsen, Elisabeth Dovern, Bart J. Biemond, Roselie M. H. Diederen, Erfan Nur   +4 more
wiley   +1 more source

Application of SS-OCTA to evaluate the effects of long-term hydroxychloroquine treatment on retinal structure and microcirculation in patients with systemic lupus erythematosus. [PDF]

BMC Ophthalmol
Li X, Xiong C, Luo S, Chen Y, Li M, Wang S, Wang Y, Wang Z, Wu R, Liao H.   +9 more
europepmc   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Peptide Lv Deficiency Adversely Impacts the Structural and Functional Integrity of the Neural Retina. [PDF]

Invest Ophthalmol Vis Sci
Owusu-Ansah K, Pham DL, Strong BC, Liberoni L, Hein TW, Kuo L, Ko ML, Ko GY.   +7 more
europepmc   +1 more source