Results 31 to 40 of about 498,360 (318)

Brain and Retinal Organoids for Disease Modeling: The Importance of In Vitro Blood–Brain and Retinal Barriers Studies

open access: yesCells, 2022
Brain and retinal organoids are functional and dynamic in vitro three-dimensional (3D) structures derived from pluripotent stem cells that spontaneously organize themselves to their in vivo counterparts.
Ilenia Martinelli   +5 more
doaj   +1 more source

Retinal remodeling in human retinitis pigmentosa

open access: yesExperimental Eye Research, 2016
Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural degenerative disease usually caused by gene defects that disrupt the function or architecture of the photoreceptors. While RP can initially be a disease of photoreceptors, there is increasing evidence that the inner retina becomes progressively disorganized as the ...
Jones, B.W.   +5 more
openaire   +2 more sources

Comparison of the Fixation Effects of Six Composite Fixatives on Retinal Tissue of Golden Hamsters

open access: yesShiyan dongwu yu bijiao yixue
Objective To compare the effects of six composite fixatives on paraffin sections of golden hamster retinal tissue, and to optimize the fixation methods for retinal tissue paraffin sections of golden hamsters.
WU Haifeng   +4 more
doaj   +1 more source

Optical coherence tomography demonstrating macular retinal nerve fiber thinning in advanced optic disc drusen

open access: yesOman Journal of Ophthalmology, 2014
Optic disc drusen (ODD) are extracellular proteinaceous excrescences in the optic nerve head. They enlarge over time and can cause damage to nerve fibers with resulting loss of visual field.
Ali Hassan, Pieter Gouws
doaj   +1 more source

Ultrafast Backbone Protonation in Channelrhodopsin-1 Captured by Polarization Resolved Fs Vis-pump—IR-Probe Spectroscopy and Computational Methods

open access: yesMolecules, 2020
Channelrhodopsins (ChR) are light-gated ion-channels heavily used in optogenetics. Upon light excitation an ultrafast all-trans to 13-cis isomerization of the retinal chromophore takes place.
Till Stensitzki   +4 more
doaj   +1 more source

Multimodal Retinal Imaging for Detection of Ischemic Stroke

open access: yesFrontiers in Aging Neuroscience, 2021
Background: This study aims to evaluate ocular changes in patients with ischemic stroke using multimodal imaging and explore the predictive value of ocular abnormalities for ischemic stroke.Methods: A total of 203 patients (ischemic stroke group, 62 ...
Lu Zhao   +6 more
doaj   +1 more source

Retinal Fluorescein Leakage in Retinitis Pigmentosa

open access: yesAmerican Journal of Ophthalmology, 1986
Of 82 consecutive patients with retinitis pigmentosa, 78 underwent fluorescein angiography using standard and special, abbreviated photographic protocols. The stereoscopic angiograms disclosed alterations of the blood-retinal barrier, primarily at the level of the retinal pigment epithelium, in 60 patients.
PIERMAROCCHI, STEFANO   +2 more
openaire   +5 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li   +9 more
wiley   +1 more source

Assembly of Natively Synthesized Dual Chromophores Into Functional Actinorhodopsin

open access: yesFrontiers in Microbiology, 2021
Microbial rhodopsin is a simple solar energy-capturing molecule compared to the complex photosynthesis apparatus. Light-driven proton pumping across the cell membrane is a crucial mechanism underlying microbial energy production. Actinobacteria is one of
Kimleng Chuon   +8 more
doaj   +1 more source

Retinal imaging in inherited retinal diseases

open access: yesAnnals of Eye Science, 2020
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population. The advances in ocular genetics, retinal imaging and molecular biology, have conspired to create the ideal environment for establishing treatments for IRD, with the first approved gene therapy and the commencement of multiple therapy trials.
Georgiou, Michalis   +2 more
openaire   +2 more sources

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