Abstract.Purpose:Malfunction of retinal blood flow or oxygenation is believed to be involved in various diseases. Among them are retinal vessel occlusions, diabetic retinopathy and glaucoma. Reliable, non‐invasive technology for retinal oxygen measurements has been scarce and most of the knowledge on retinal oxygenation comes from animal studies.
openaire +5 more sources
Microscopic Inner Retinal Hyper-reflective Phenotypes in Retinal and Neurologic Disease [PDF]
Purpose. We surveyed inner retinal microscopic features in retinal and neurologic disease using a reflectance confocal adaptive optics scanning light ophthalmoscope (AOSLO). Methods. Inner retinal images from 101 subjects affected by one of 38 retinal or
Carroll, Joseph+9 more
core +2 more sources
Retinal prostheses in degenerative retinal diseases
Degenerative retinal diseases may lead to significant loss of vision. Age-related macular degeneration (AMD) and retinitis pigmentosa (RP), which eventually affect the photoreceptors, are the two most common retinal degenerative diseases. Once the photoreceptorcells are lost, there are no known effective therapies for AMD or RP.
Shih-Jen Chen+9 more
openaire +3 more sources
Interactive Blood Vessel Segmentation from Retinal Fundus Image Based on Canny Edge Detector
Optometrists, ophthalmologists, orthoptists, and other trained medical professionals use fundus photography to monitor the progression of certain eye conditions or diseases. Segmentation of the vessel tree is an essential process of retinal analysis.
Alexander Ze Hwan Ooi+8 more
doaj +1 more source
Segmentation of Retinal Blood Vessels Using Deep Learning [PDF]
The morphology of retinal blood vessels can indicate various diseases in the human body, and researchers have been working on automatic scanning and segmentation of retinal images to aid diagnosis. This project compares the performance of four neural network architectures in segmenting retinal images, using a combined dataset from different databases ...
arxiv
The demosponge Suberites domuncula has been described to contain high levels of a proteinaceous toxin, Suberitine, that displays haemolytic activityIn the present study this 7–8 kDa polypeptide has been isolated and was shown to exhibit also cytotoxic ...
Heinz C. Schröder+5 more
doaj +1 more source
Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C.+5 more
core +1 more source
Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. [PDF]
BACKGROUND:Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss.
Aktas, Orhan+18 more
core +1 more source
Functional Imaging of the Outer Retinal Complex using High Fidelity Imaging Retinal Densitometry [PDF]
We describe a new technique, high fidelity Imaging Retinal Densitometry (IRD), which probes the functional integrity of the outer retinal complex. We demonstrate the ability of the technique to map visual pigment optical density and synthesis rates in ...
Atkinson, D.+11 more
core +3 more sources
Automated segmentation of retinal fluid volumes from structural and angiographic optical coherence tomography using deep learning [PDF]
Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired on one eye by a 70-kHz OCT commercial AngioVue system (RTVue-XR; Optovue, Inc.) from 51 participants in a clinical ...
arxiv +1 more source