Abstract.Purpose:Malfunction of retinal blood flow or oxygenation is believed to be involved in various diseases. Among them are retinal vessel occlusions, diabetic retinopathy and glaucoma. Reliable, non‐invasive technology for retinal oxygen measurements has been scarce and most of the knowledge on retinal oxygenation comes from animal studies.
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Retinal arterioles narrow with increasing duration of anti-retroviral therapy in HIV infection: a novel estimator of vascular risk in HIV? [PDF]
OBJECTIVES: HIV infection is associated with an increased risk of age-related morbidity mediated by immune dysfunction, atherosclerosis and inflammation.
Pathai, Sophia +29 more
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Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Kerstin N. Euler +25 more
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Retinal Fluorescein Leakage in Retinitis Pigmentosa
Of 82 consecutive patients with retinitis pigmentosa, 78 underwent fluorescein angiography using standard and special, abbreviated photographic protocols. The stereoscopic angiograms disclosed alterations of the blood-retinal barrier, primarily at the level of the retinal pigment epithelium, in 60 patients.
PIERMAROCCHI, STEFANO +2 more
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Uptake and metabolism of retinol (vitamin A) in the isolated perfused rat liver
The isolated perfused liver was employed to study various aspects of retinol-C14 metabolism. The rate of uptake of retinol, retinal, retinoic acid, and retinol acetate was rapid (first-order rate constant, k = 0.12–0.16 min−1) during the first 3–10 min ...
Richard D. Zachman, James Allen Olson
doaj +1 more source
Retinal cell transplantation in retinitis pigmentosa
Retinitis pigmentosa is the most common hereditary retinal disease. Dietary supplements, neuroprotective agents, cytokines, and lately, prosthetic devices, gene therapy, and optogenetics have been employed to slow down the retinal degeneration or improve light perception.
Tongalp H Tezel, Adam Ruff
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Anatomic Success of Scleral Buckling for Rhegmatogenous Retinal Detachment - A Retrospective Study of 524 Cases [PDF]
Background/Aim: Our purpose was to investigate the anatomic success of scleral buckling surgery for rhegmatogenous retinal detachment. Material and Methods: A total of 524 consecutive patients were retrospectively analysed.
Haritoglou, Christos +3 more
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Laser Photocoagulation for Retinal Detachments and Retinal Tears in Cytomegalovirus Retinitis
Retinal detachment complicates the course of cytomegalovirus (CMV) retinitis in nearly 30% of human immunodeficiency virus-infected patients. The study goal was to evaluate laser photocoagulation in the treatment of CMV retinitis-related retinal detachments and retinal tears.Nonrandomized, observational cohort study.Sixty-three patients with CMV ...
J L, Davis, J, Hummer, W J, Feuer
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Early stages of retinal development depend on Sec13 function [PDF]
ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi +7 more
core +1 more source
Retinal prostheses in degenerative retinal diseases
Degenerative retinal diseases may lead to significant loss of vision. Age-related macular degeneration (AMD) and retinitis pigmentosa (RP), which eventually affect the photoreceptors, are the two most common retinal degenerative diseases. Once the photoreceptorcells are lost, there are no known effective therapies for AMD or RP.
Lin, Tai-Chi +6 more
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