Results 61 to 70 of about 712,970 (307)

Factors Associated With Retinal Vessel Diameters in an Elderly Population: the Thessaloniki Eye Study [PDF]

open access: yes, 2019
Purpose: To identify the factors associated with retinal vessel diameters in the population of the Thessaloniki Eye Study. Methods: Cross-sectional population-based study (age ≥ 60 years). Subjects with glaucoma, late age-related macular degeneration,
Anastasopoulos, Eleftherios   +9 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Automatic Detection of Exudates in Digital Color Fundus Images Using Superpixel Multi-Feature Classification

open access: yesIEEE Access, 2017
Exudates can be regarded as one of the most prevalent clinical signs of diabetic retinopathy, and the detection of exudates has important clinical significance in diabetic retinopathy diagnosis.
Wei Zhou   +3 more
doaj   +1 more source

The Role of Graphene Monolayers in Enhancing the Yield of Bacteriorhodopsin Photostates for Optical Memory Applications

open access: yesApplied Sciences, 2021
Bacteriorhodopsin (bR) is a photoactive protein that has gained increasing importance as a tool for optical memory storage due to its remarkable photochemical and thermal stability.
Roma Patel   +2 more
doaj   +1 more source

Retinal micro-vascular and aortic macro-vascular changes in postmenopausal women with primary hyperparathyroidism [PDF]

open access: yes, 2018
Aim of the study was to evaluate the micro and macro-vascular changes in patients with primary hyperparathyroidism (PHPT) compared to controls. 30 postmenopausal PHPT women (15 hypertensive and 15 normotensive) and 30 normotensive controls underwent ...
Biamonte, Federica   +8 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. [PDF]

open access: yes, 2004
Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor ...
Brodie, Scott E   +5 more
core   +1 more source

Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]

open access: yes, 1991
During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Adler   +55 more
core   +1 more source

Extraocular Muscle Imbalance and Outcomes of Scleral Buckling Surgery for Primary Rhegmatogenous Retinal Detachment [PDF]

open access: yes, 2020
Objective: The objective was to study the muscle imbalance, restrictive motility in unlike gazes and the outcomes of the scleral buckling surgery for rhegmatogenous retinal detachment.
Kawish, A. B. (Ayesha)   +2 more
core   +1 more source

Retinal remodeling

open access: yesJapanese Journal of Ophthalmology, 2012
Retinal photoreceptor degeneration takes many forms. Mutations in rhodopsin genes or disorders of the retinal pigment epithelium, defects in the adenosine triphosphate binding cassette transporter, ABCR gene defects, receptor tyrosine kinase defects, ciliopathies and transport defects, defects in both transducin and arrestin, defects in rod cyclic ...
B W, Jones   +5 more
openaire   +3 more sources

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