Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase ß subunit [PDF]
, 1992 The ß subunit of the cGMP phosphodiesterase (PDE) gene has been identified as the candidate gene for retinal degeneration in the rd mouse. To study the molecular mechanisms underlying degeneration and the potential for gene repair, we have expressed a ...
Applebury, Meredithe L. +5 more
core
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Peripheral retinal degeneration. [PDF]
British Journal of Ophthalmology, 1967 Wc H, London, Tavistock Square
openaire +3 more sources
The Postbiotic Potential of Microalgae
Food Frontiers, EarlyView.Description of “Microalgal Postbiotic” following ISAPP Consensus (Salminen et al. 2021b) (Icons produced with Biorender) ABSTRACT The International Scientific Association for Probiotics and Prebiotics (ISAPP) has defined postbiotics as “preparations of inanimate microorganisms and/or their components that confer a health benefit on the host ...
Francesco Martelli +2 more
wiley +1 more source
Vision Changes After Head and Neck Cancer Treatment
Head &Neck, EarlyView.ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang +7 more
wiley +1 more source
Frequency of the codon 807 mutation in the cGMP phosphodiesterase beta-subunit gene in Irish setters and other dog breeds with hereditary retinal degeneration [PDF]
, 1999 G.D. Aguirre
openalex +1 more source
A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis
Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo +7 more
wiley +1 more source
Progress of non‐motor symptoms in early‐onset Parkinson's disease
Ibrain, EarlyView.This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang +5 more
wiley +1 more source
Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations. [PDF]
, 2019 PurposeTo determine whether high-resolution retinal imaging measures of macular structure correlate with visual function over 36 months in retinal degeneration (RD) patients and normal subjects.MethodsTwenty-six eyes of 16 RD patients and 16 eyes of 8 ...
Baldwin, Angela +8 more
core +1 more source
Organoid‐tissue extracellular vesicles
Interdisciplinary Medicine, EarlyView.Abstract Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological state of the tissue microenvironment.
Han Liu +6 more
wiley +1 more source